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COL18A1 Protein, Human, Recombinant (His)

COL18A1 Protein, Human, Recombinant (His)

产品编号 TMPH-01118
别名: COL18A1, Collagen alpha-1(XVIII) chain

COL18A1 Protein, Human, Recombinant (His) is expressed in Yeast.

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COL18A1 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,470 20日内发货
100 μg ¥ 2,780 20日内发货
1 mg ¥ 11,900 20日内发货
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产品目录号及名称: COL18A1 Protein, Human, Recombinant (His) (TMPH-01118)
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生物活性
技术参数
产品性质
产品描述 COL18A1 Protein, Human, Recombinant (His) is expressed in Yeast.
种属 Human
表达系统 Yeast
标签 N-terminal 6xHis-tagged
蛋白编号 P39060
别名 COL18A1, Collagen alpha-1(XVIII) chain
氨基酸序列 QPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1578-1754 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 21.3 kDa (predicted)
缓冲液 Tris-based buffer,50% glycerol
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.; May regulate extracellular matrix-dependent motility and morphogenesis of endothelial and non-endothelial cells; the function requires homotrimerization and implicates MAPK signaling.; Potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Inhibits VEGFA-induced endothelial cell proliferation and migration. Seems to inhibit VEGFA-mediated signaling by blocking the interaction of VEGFA to its receptor KDR/VEGFR2. Modulates endothelial cell migration in an integrin-dependent manner implicating integrin ITGA5:ITGB1 and to a lesser extent ITGAV:ITGB3 and ITGAV:ITGB5. May negatively regulate the activity of homotrimeric non-collagenous domain 1.

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Keywords

COL18A1 Protein, Human, Recombinant (His) COL18A1 Collagen alpha-1(XVIII) chain recombinant recombinant-proteins proteins protein

 

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