CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,400 | 5日内发货 | ||
500 μg | ¥ 13,600 | 5日内发货 | ||
1 mg | ¥ 22,700 | 5日内发货 |
生物活性 | Immobilized Human CLEC12A at 0.5μg (100μl/Well) on the plate. Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA. |
产品描述 | CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. |
种属 | Human |
表达系统 | HEK293 |
标签 | N-His |
蛋白编号 | Q5QGZ9-2 |
别名 | CLECSF7, CLL-1, PRO34150, CLL1, DLEC, CLEC12A, DCAL2, CLECSF11, MICL, CD303, DCAL-2, HECL, CD371 |
蛋白构建 | Recombinant Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus. It contains His65-Ala265.[Accession |Q5QGZ9-2] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 38-55 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. |
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CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) PRO 34150 CLECSF7 CLECSF 7 CD 303 CLECSF-7 CLL 1 CD 371 CLL-1 PRO34150 CLL1 DLEC CLECSF 11 CD-371 CLEC12A DCAL2 PRO-34150 CLECSF11 MICL CD-303 CD303 DCAL-2 CLECSF-11 HECL CD371 DCAL 2 recombinant recombinant-proteins proteins protein