Claudin-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.9 kDa and the accession number is O95484.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 6,390 | 5日内发货 | ||
100 μg | ¥ 13,400 | 5日内发货 | ||
500 μg | ¥ 47,400 | 5日内发货 |
生物活性 | Immobilized Human CLDN9-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) can bind Anti-Human CLDN9 Antibody,Human IgG1, the EC50 is 1-10 ng/mL. |
产品描述 | Claudin-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.9 kDa and the accession number is O95484. |
种属 | Human |
表达系统 | HEK293 |
标签 | Tag Free |
蛋白编号 | O95484 |
蛋白构建 | A DNA sequence encoding the human CLDN9 (O95484) (Met1-Val217) was expressed. |
分子量 | 22.9 kDa (predicted) |
内毒素 | < 1.0 EU per μg protein as determined by the LAL method. |
缓冲液 | Supplied as sterile 50mM Hepes, 150mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
It is supplied and shipped as Solution with dry ice. |
研究背景 | Claudin-9 (CLDN9) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and a cytoplasmic C tail. CLDN9 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It forms heterotypic interactions with other claudins to create cation-selective channels in the kidney and may contribute to the maintenance of alveolar barrier function in the lung. Deficiency is shown to be associated with autosomal recessive deafness, DFNB116. CLDN9 expression has been shown to be upregulated in certain types of cancer, such as endometrial cancer and hepatocellular carcinoma, and its knockdown has been found to reduce cell proliferation and migration in vitro. |
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recombinant recombinant-proteins proteins protein