Claudin-4 Protein-VLP, Human, Recombinant

Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

规格	价格/CNY		数量
100 μg	￥ 10,300	5日内发货
500 μg	￥ 41,500	5日内发货
1 mg	￥ 69,200	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 10,300

5日内发货

500 μg

￥ 41,500

5日内发货

1 mg

￥ 69,200

5日内发货

生物活性

Immobilized Human Claudin 4 VLP at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.

产品描述

种属	Human
表达系统	HEK293
蛋白编号	O14493
别名	Claudin4, CLDN4, Claudin-4, CPETR1, CPE-R, WBSCR8, CPE R
蛋白构建	Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293. It contains Met1-Val209.[Accession \|O14493]
蛋白纯度	> 95% as determined by HPLC
分子量	The target protein has a predicted MW of 23.31 kDa.

内毒素	Less than 1EU per μg by the LAL method.
缓冲液	Supplied as 0.22μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
存储	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.