CISH Protein, Human, Recombinant (GST) is expressed in E. coli.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 1,320 | 20日内发货 | ||
100 μg | ¥ 2,470 | 20日内发货 | ||
1 mg | ¥ 10,700 | 20日内发货 |
产品描述 | CISH Protein, Human, Recombinant (GST) is expressed in E. coli. |
种属 | Human |
表达系统 | E. coli |
标签 | N-terminal GST-tagged |
蛋白编号 | Q9NSE2 |
别名 | Suppressor of cytokine signaling, Cytokine-inducible SH2-containing protein, SOCS, CIS-1, CIS, CISH, G18 |
氨基酸序列 | MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. |
蛋白构建 | 1-258 aa |
蛋白纯度 | > 90% as determined by SDS-PAGE. |
分子量 | 55.7 kDa (predicted) |
缓冲液 | Tris-based buffer,50% glycerol |
复溶方法 | A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
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CISH Protein, Human, Recombinant (GST) Suppressor of cytokine signaling Cytokine-inducible SH2-containing protein SOCS CIS-1 CIS CISH G18 recombinant recombinant-proteins proteins protein