CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

规格	价格/CNY		数量
100 μg	￥ 3,850	5日内发货
500 μg	￥ 15,400	5日内发货
1 mg	￥ 25,700	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 3,850

5日内发货

500 μg

￥ 15,400

5日内发货

1 mg

￥ 25,700

5日内发货

产品描述

种属	Human
表达系统	HEK293
标签	C-hFc
蛋白编号	Q12864
别名	HPT-1, P130, MGC138218, LI-cadherin, FLJ26931, cadherin-16, Cdh17, CDH16, BILL-cadherin, Cadherin-17, MGC142024
蛋白构建	Recombinant Human CDH17/Cadherin 17 Domain 6-7 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ser567-Gly777.[Accession \|Q12864]
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	The protein has a predicted MW of 49.29 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

内毒素	Less than 1EU per μg by the LAL method.
缓冲液	Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
存储	-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.