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CD58 Protein, Human, Recombinant (hFc)

CD58 Protein, Human, Recombinant (hFc)

产品编号 TMPY-03408
别名: CD58, ag3, LFA-3, LFA3, CD58 molecule

CD58 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is Q9BRW0.

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CD58 Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货
1 mg ¥ 29,100 5日内发货
千万补贴 助力科研
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产品目录号及名称: CD58 Protein, Human, Recombinant (hFc) (TMPY-03408)
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生物活性
技术参数
产品性质
参考文献
生物活性 1. Measured by its binding ability in a functional ELISA. Immobilized human CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 μg/ml. 2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.10 μg/ml.
产品描述 CD58 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is Q9BRW0.
种属 Human
表达系统 HEK293
标签 hFc
蛋白编号 Q9BRW0
别名 CD58, ag3, LFA-3, LFA3, CD58 molecule
蛋白构建 A DNA sequence encoding the human CD58 (Q9BRW0) (Met1-Arg215) was expressed with the Fc region of human IgG1 at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 48.5 kDa (predicted)
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method
缓冲液 Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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Keywords

CD58 Protein, Human, Recombinant (hFc) LFA 3 CD58 ag3 CD 58 LFA-3 LFA3 CD58 molecule CD-58 recombinant recombinant-proteins proteins protein

 

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