CD40 Protein, Mouse, Recombinant (His)

CD40 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.81 kDa and the accession number is P27512-1.

规格	价格/CNY		数量
50 μg	￥ 2,260	现货
100 μg	￥ 4,010	5日内发货
200 μg	￥ 7,090	5日内发货
500 μg	￥ 15,000	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 2,260

现货

100 μg

￥ 4,010

5日内发货

200 μg

￥ 7,090

5日内发货

500 μg

￥ 15,000

5日内发货

生物活性

1.Measured by its binding ability in a functional ELISA. Immobilized CD40 Protein, Mouse, (ECD, His Tag) at 2 μg/mL (100 μL/well) can bind CD40 Ligand Protein, Human, (hFc Tag), the EC50 of CD40 L-hFc is 70-180 ng/mL. 2.Loaded Recombinant Mouse CD40 Protein, His Tag on His1K Biosensor, can bind Recombinant Mouse CD40 Ligand Protein, hFc Tag with an affinity constant of 87.2nM as determined in BLI assay (Routinely tested).

TargetMol Bioactive

产品描述

CD40 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.81 kDa and the accession number is P27512-1.

种属	Mouse
表达系统	HEK293
标签	His
蛋白编号	P27512-1
别名	Bp50, HIGM1, TRAP, T-BAM, GP39, AI326936, p50, IGM, CD40 molecule, TNF receptor superfamily member 5, Tnfrsf5, IMD3
蛋白构建	A DNA sequence encoding the mouse CD40 (NP_035741.2) (Met1-Arg193) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度	≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
分子量	20.81 kDa (predicted)

内毒素	< 1.0 EU per μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy