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CD40 Protein, Canine, Recombinant (hFc)

CD40 Protein, Canine, Recombinant (hFc)

产品编号 TMPY-03907
别名: CD40 molecule, TNF receptor superfamily member 5

CD40 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.1 kDa and the accession number is Q7YRL5.

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CD40 Protein, Canine, Recombinant (hFc)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
千万补贴 助力科研
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产品目录号及名称: CD40 Protein, Canine, Recombinant (hFc) (TMPY-03907)
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参考文献
生物活性 Testing in progress
产品描述 CD40 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.1 kDa and the accession number is Q7YRL5.
种属 Canine
表达系统 HEK293
标签 hFc
蛋白编号 Q7YRL5
别名 CD40 molecule, TNF receptor superfamily member 5
蛋白构建 A DNA sequence encoding the canine CD40 (Q7YRL5) (Met1-Ala194) was expressed with the Fc region of human IgG1 at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 46.1 kDa (predicted)
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method
缓冲液 Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

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Keywords

CD40 Protein, Canine, Recombinant (hFc) CD40 molecule, TNF receptor superfamily member 5 recombinant recombinant-proteins proteins protein

 

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