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CD20 Protein, Human, Recombinant (His & Avi), Biotinylated

CD20 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPK-00184
别名: MS4A-1, CD20, B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, Bp35, MS4A1

B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.

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CD20 Protein, Human, Recombinant (His & Avi), Biotinylated
规格 价格/CNY 货期 数量
100 μg ¥ 5,180 5日内发货
500 μg ¥ 20,700 5日内发货
1 mg ¥ 34,600 5日内发货
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产品目录号及名称: CD20 Protein, Human, Recombinant (His & Avi), Biotinylated (TMPK-00184)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Biotinylated Human CD20, His Tag at 1μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 87.3ng/ml determined by ELISA.
产品描述 B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
种属 Human
表达系统 E. coli
标签 C-His-Avi
蛋白编号 P11836-1
别名 MS4A-1, CD20, B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, Bp35, MS4A1
蛋白构建 Recombinant Biotinylated Human CD20/MS4A1 Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus. It contains Ile141-Ser188.[Accession |P11836-1]
蛋白纯度 > 95% as determined by Tris-Bis PAGE
分子量 The protein has a predicted MW of 16.8 kDa same as Tris-Bis PAGE result.
内毒素 Less than 1EU per μg by the LAL method.
缓冲液 Supplied as 0.22μm filtered solution in 20mM PB ,10% Glycerol (pH 7.0).
存储

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.

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Keywords

CD20 Protein, Human, Recombinant (His & Avi), Biotinylated MS4A-1 CD20 B-lymphocyte surface antigen B1 CD 20 Membrane-spanning 4-domains subfamily A member 11 Leukocyte surface antigen Leu-16 Bp35 MS4A1 CD-20 recombinant recombinant-proteins proteins protein

 

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