CD155/PVR Protein, Mouse, Recombinant (mFc)

CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094.

规格	价格/CNY		货期	数量
50 μg	￥ 2,270	现货
1 mg	￥ 24,900	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 2,270

现货

1 mg

￥ 24,900

5日内发货

生物活性

1. Measured by its binding ability in a functional ELISA. Immobilized TIGIT Protein, Human, Recombinant (ECD, His Tag) at 2 μg/ml (100 μl/well) can bind CD155/PVR Protein, Mouse, Recombinant (mFc Tag), the EC50 of CD155/PVR Protein, Mouse, Recombinant (mFc Tag) is 25-140 ng/mL. 2. Immobilized mouse CD155 (mFc Tag) at 2 μg/mL (100μL/well) can bind Mouse TIGIT-His, HPLC-verified, the EC50 of Mouse TIGIT-His, HPLC-verified is 300-900 ng/mL.

产品描述

CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094.

种属	Mouse
表达系统	HEK293 Cells
标签	C-mFc
蛋白编号	Q8K094
别名	Taa1, 3830421F03Rik, poliovirus receptor, necl-5, D7Ertd458e, HVED, CD155, PVS, mE4, Tage4
蛋白构建	The Mouse PVR (NP_081790.1) (Met1-Arg345) was expressed with the Fc region of Mouse IgG2a at the C-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	60.78 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy