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CD147 Protein, Human, Recombinant (aa 138-323, hFc)

产品编号 TMPH-00998

别名: HAb18G, BSG, Basigin, CD147, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, Hepatoma-associated antigen, 5F7, Collagenase stimulatory factor

CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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CD147 Protein, Human, Recombinant (aa 138-323, hFc)

规格	价格/CNY		货期	数量
20 μg	￥ 2,340		20日内发货
100 μg	￥ 6,570		20日内发货
1 mg	￥ 27,600		20日内发货

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产品描述	CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.

种属	Human
表达系统	HEK293
标签	C-terminal hFc-tagged
蛋白编号	P35613
别名	HAb18G, BSG, Basigin, CD147, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, Hepatoma-associated antigen, 5F7, Collagenase stimulatory factor
氨基酸序列	EPGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLA Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建	138-323 aa
蛋白纯度	> 85% as determined by SDS-PAGE.
分子量	49.3 kDa (predicted)

缓冲液	Tris-based buffer,50% glycerol
复溶方法	A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.; Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells. Plays an important role in targeting monocarboxylate transporters SLC16A1/GLUT1, SLC16A11 and SLC16A12 to the plasma membrane. Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling. Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA (isoform VEGF-165 and VEGF-121) and KDR/VEGFR2 in endothelial cells. Plays a key role in regulating tumor growth, invasion, metastasis and neoangiogenesis by stimulating the production and release of extracellular matrix metalloproteinases and KDR/VEGFR2 by both tumor cells and stromal cells (fibroblasts and endothelial cells).; (Microbial infection) Erythrocyte receptor for P.falciparum RH5 which is essential for erythrocyte invasion by the merozoite stage of P.falciparum isolates 3D7 and Dd2.; (Microbial infection) Erythrocyte receptor for P.falciparum RH5 which is essential for erythrocyte invasion by the merozoite stage of P.falciparum isolates 3D7, Dd2, 7G8 and HB3. Binding of P.falciparum RH5 results in BSG dimerization which triggers an increase in intracellular Ca(2+) in the erythrocyte. This essential step leads to a rearrangement of the erythrocyte cytoskeleton required for the merozoite invasion.; (Microbial infection) Can facilitate human SARS coronavirus (SARS-CoV-1) infection via its interaction with virus-associated PPIA/CYPA.; (Microbial infection) Can facilitate HIV-1 infection via its interaction with virus-associated PPIA/CYPA.; (Microbial infection) First described as a receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is not required for SARS-CoV-2 infection.; (Microbial infection) Acts as a receptor for measles virus.; (Microbial infection) Promotes entry of pentamer-expressing human cytomegalovirus (HCMV) into epithelial and endothelial cells.

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Keywords

CD147 Protein, Human, Recombinant (aa 138-323, hFc) HAb18G BSG Basigin CD147 EMMPRIN Extracellular matrix metalloproteinase inducer Leukocyte activation antigen M6 Hepatoma-associated antigen 5F7 Collagenase stimulatory factor recombinant recombinant-proteins proteins protein

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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