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CD123 Protein, Cynomolgus, Recombinant (His)

CD123 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPJ-00639
别名: Interleukin-3 receptor subunit α, IL-3R subunit α, IL-3R-α, Interleukin-3 receptor subunit alpha, IL-3R-alpha, IL-3RA, IL-3R subunit alpha, IL-3 receptor subunit α, IL-3 receptor subunit alpha

CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.

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CD123 Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 550 5日内发货
50 μg ¥ 1,670 5日内发货
500 μg ¥ 13,700 5日内发货
1 mg ¥ 20,500 5日内发货
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产品目录号及名称: CD123 Protein, Cynomolgus, Recombinant (His) (TMPJ-00639)
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产品描述 CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 G8F3K3
别名 Interleukin-3 receptor subunit α, IL-3R subunit α, IL-3R-α, Interleukin-3 receptor subunit alpha, IL-3R-alpha, IL-3RA, IL-3R subunit alpha, IL-3 receptor subunit α, IL-3 receptor subunit alpha
氨基酸序列 Arg18-Arg302
蛋白构建 Arg18-Arg302
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 50-65 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage‑committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL‑3 with low affinity. The beta subunit does not bind IL‑3 by itself but is required for the high‑affinity binding of IL‑3 to the heterodimeric receptor complex.

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Keywords

CD123 Protein, Cynomolgus, Recombinant (His) Interleukin-3 receptor subunit α IL-3R subunit α IL-3R-α Interleukin-3 receptor subunit alpha IL-3R-alpha IL-3RA IL-3R subunit alpha IL-3 receptor subunit α IL-3 receptor subunit alpha recombinant recombinant-proteins proteins protein

 

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