Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 1,170 | 5日内发货 | ||
50 μg | ¥ 3,470 | 5日内发货 | ||
500 μg | ¥ 13,200 | 5日内发货 | ||
1 mg | ¥ 18,900 | 5日内发货 |
产品描述 | Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers. |
种属 | Human |
表达系统 | E. coli |
标签 | N-6His |
蛋白编号 | Q8WYN0 |
别名 | ATG4A, Autophagin-2, AUT-Like 2 Cysteine Endopeptidase, APG4A, Autophagy-Related Protein 4 Homolog A, Autophagy-Related Cysteine Endopeptidase 2, hAPG4A, Cysteine Protease ATG4A, AUTL2 |
氨基酸序列 | Met1-Val398 |
蛋白构建 | Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus. |
蛋白纯度 | Greater than 80% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 40-55 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers. |
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ATG4A Protein, Human, Recombinant (His) AUTL-2 AUTL 2 ATG4A Autophagin-2 AUT-Like 2 Cysteine Endopeptidase APG4A Autophagy-Related Protein 4 Homolog A Autophagy-Related Cysteine Endopeptidase 2 hAPG4A Cysteine Protease ATG4A AUTL2 recombinant recombinant-proteins proteins protein