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ASH2L Protein, Human, Recombinant (His & SUMO)

ASH2L Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-02105
别名: ASH2-like protein, ASH2L, ASH2L1, Set1/Ash2 histone methyltransferase complex subunit ASH2

Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.

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ASH2L Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: ASH2L Protein, Human, Recombinant (His & SUMO) (TMPH-02105)
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产品描述 Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
种属 Human
表达系统 E. coli
标签 N-terminal 6xHis-SUMO-tagged
蛋白编号 Q9UBL3
别名 ASH2-like protein, ASH2L, ASH2L1, Set1/Ash2 histone methyltransferase complex subunit ASH2
氨基酸序列 MDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1-534 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 76.2 kDa (predicted)
缓冲液 Tris-based buffer,50% glycerol
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.

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Keywords

ASH2L Protein, Human, Recombinant (His & SUMO) ASH2-like protein ASH2L ASH2L1 Set1/Ash2 histone methyltransferase complex subunit ASH2 recombinant recombinant-proteins proteins protein

 

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