Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 4,470 | 现货 | ||
200 μg | ¥ 7,630 | 5日内发货 | ||
500 μg | ¥ 15,450 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet. |
种属 | Human |
表达系统 | HEK293 |
标签 | His |
蛋白编号 | P06727 |
别名 | apolipoprotein A-IV |
蛋白构建 | A DNA sequence encoding the human APOA4 (NP_000473.2) (Met1-Ser396) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 |
> 95 % as determined by SDS-PAGE.
|
分子量 | Approxiamtely 44.8 kDa |
内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His) apolipoprotein A-IV recombinant recombinant-proteins proteins protein