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AG-2 Protein, Human, Recombinant (His)

AG-2 Protein, Human, Recombinant (His)

产品编号 TMPJ-00056
别名: HPC8, AG2, AG-2, hAG-2, Anterior Gradient Protein 2 Homolog, AGR2, Secreted Cement Gland Protein XAG-2 Homolog

Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.

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AG-2 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: AG-2 Protein, Human, Recombinant (His) (TMPJ-00056)
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产品描述 Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
种属 Human
表达系统 Human Cells
标签 C-6His
蛋白编号 O95994
别名 HPC8, AG2, AG-2, hAG-2, Anterior Gradient Protein 2 Homolog, AGR2, Secreted Cement Gland Protein XAG-2 Homolog
氨基酸序列 Arg21-Leu175
蛋白构建 Recombinant Human Anterior Gradient Protein 2 Homolog is produced by our Mammalian expression system and the target gene encoding Arg21-Leu175 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. Greater than 90% as determined by SEC-HPLC.
分子量 18 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 10%Glycerol, 0.01%Tween80, pH8.0.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.

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Keywords

AG-2 Protein, Human, Recombinant (His) AG 2 HPC8 AG2 AG-2 AGR-2 HPC-8 hAG-2 Anterior Gradient Protein 2 Homolog HPC 8 AGR 2 AGR2 Secreted Cement Gland Protein XAG-2 Homolog recombinant recombinant-proteins proteins protein

 

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