The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 1,470 | 5日内发货 | ||
50 μg | ¥ 3,250 | 5日内发货 | ||
500 μg | ¥ 23,700 | 5日内发货 | ||
1 mg | ¥ 35,600 | 5日内发货 |
生物活性 | Measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic). The specific activity is 136.6pmol/min/μg. (Regularly tested) |
产品描述 | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
种属 | SARS-CoV-2 |
表达系统 | E. coli |
标签 | Tag Free |
蛋白编号 | P0DTC1 |
别名 | M Proteinase, 3C-like Proteinase, 3CL Proteinase |
氨基酸序列 | Ser3264-Gln3569 |
蛋白构建 | Recombinant SARS-CoV-2 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser3264-Gln3569 is expressed. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 30 kDa, reducing conditions |
内毒素 | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM EDTA, pH7.3. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant M Proteinase 3C-like Proteinase 3CL Proteinase recombinant recombinant-proteins proteins protein