| TN1613 |
(-)-Epipinoresinol |
(-)-Epipinoresinol is a natural product |
| TN1974 |
Negsehisandrin G |
Negsehisandrin G is a natural product |
| TN2062 |
Phyllanthin |
Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp. |
| TN1915 |
Matairesinol 4'-O-beta-gentiobioside |
Matairesinol 4'-O-beta-gentiobioside is a natural product from Trachelospermum jasminoides. |
| T3866 |
Anwuligan |
Anwuligan is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. |
| TN1506 |
Clemastanin B |
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and b...
|
| TN1009 |
Epimagnolin B |
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the ...
|
| TN2311 |
Wulignan A1 |
Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) ac...
|
| TN1594 |
DL-Syringaresinol |
(+)-Syringaresinol shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 microg/ml. |
| TN1357 |
Acetylepipodophyllotoxin |
Acetylepipodophyllotoxin has insecticidal activity. |
| TN2187 |
Schisanwilsonin H |
Schisanwilsonin H is a natural product |
| TN2188 |
Schisanwilsonin I |
Schisanwilsonin D, and schisantherin C show anti-HBV activity. |
| TN1710 |
Gomisin S |
Gomisin S is a natural product |
| TN1760 |
Icariside E5 |
Icariside E5 may have antioxidant property that strengthen the importance of peppers in the Mediterranean diet. |
| T5691 |
Paulownin |
Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity. |
| TN2322 |
Yangambin |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a per...
|
| TN1318 |
6-O-benzoylgomisin O |
6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera. |
| T5S1959 |
Asarinin |
1. (-)-Asarinin shows antibacterial activity. |
| T5S0483 |
(-)-Syringaresnol-4-O-beta-D-apiofuranos |
It is a lignan glycosides from the bark of Albizzia myriophylla. |
| TN1598 |
Dunnianol |
Dunnianol, macranthol and isodunnianol have anti-inflammatory activity, they can increase NAG-1(multiple targets related to inflammation) activity 1.5-3.0 fold ...
|
| TN2174 |
Salvianolic acid E |
Salvianolic acid E is a natural product from Salvia miltiorrhiza Bge. |
| T3415 |
Secoisolariciresinol diglucoside |
Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol Diglucoside (2...
|
| TN1815 |
Kadsulignan L |
Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC...
|
| T3S0027 |
Picropodophyllotoxin |
Picropodophyllin is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth ...
|
| T3S1541 |
Rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m |
|
| TN1767 |
Interiotherin A |
Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL. |
| TN1087 |
Deoxypodophyllotoxin |
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflamma...
|
| TN1117 |
Veraguensin |
Veraguensin shows activity against trypomastigote T. cruzi., it shows high antileishmanial activity. |
| TN2268 |
Tetrahydromagnolol |
Tetrahydromagnolol can activate cannabinoid (CB) receptors. |
| TN2249 |
(+)-Syringaresinol |
(+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2. |
| TN1428 |
(+)-Balanophonin |
(+)-Balanophonin exhibits marginal inhibition on the proliferation of OPM2 and RPMI-8226 cells. |
| TN1103 |
Diphyllin |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. |
| TN1612 |
(+)-Epipinoresinol |
(+)-Epipinoresinol is a natural product |
| T6S1543 |
Dehydrodiisoeugenol |
1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated ...
|
| TN1853 |
Lariciresinol |
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel ant...
|
| TN1654 |
Futoquinol |
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng. |
| T2S0531 |
Pinoresinol dimethyl ether |
|
| TN1392 |
Anhydrosecoisolariciresinol |
Anhydrosecoisolariciresinol can significantly decrease the growth of human breast cancer MCF-7 and MDA-MB-231 cell lines at 50 and 100 microM. |
| TN2197 |
Secoisolariciresinol |
Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulatio...
|
| T3857 |
Magnolin |
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory ...
|
| T5S2178 |
Fargesin |
1. Fargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves ...
|
| TN1900 |
(-)-Lyoniresinol |
(-)-Lyoniresinol has antioxidant activity. |
| T0132 |
Etoposide |
Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50: 60.3 μM). |
| T3855 |
Tracheloside |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43...
|
| TN1757 |
Hypophyllanthin |
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice. |
| TN1834 |
Kobusin |
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflamma...
|
| TN1505 |
Clemaphenol A |
Clemaphenol A is a natural product from Cynanchum auriculatum. |
| TN1715 |
Guaiacin |
(+)-Guaiacin has significant neuroprotective, and anti-inflammatory activities, it can inhibit cyclooxygenase (COX)-1 and COX-2. |
| TN2070 |
Picropodophyllol |
Picropodophyllol is a natural product |
| T3662 |
Eleutheroside E |
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannu...
|
| T2S0029 |
4'-Demethylpodophyllotoxin |
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines. |
| TN1919 |
Medioresinol |
Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in t...
|
| TN1396 |
Arctigenin 4'-O-beta-gentiobioside |
Arctigenin 4'-O-beta-gentiobioside is a natural product from Trachelospermum jasminoides. |
| TN1610 |
Epimagnolin A |
Epimagnolin A affects the transport activity of ABCB1(a major transmembrane efflux pump belonging to the ABC transporter superfamily), it also exhibits growth i...
|
| TN1701 |
Glycosmisic acid |
Glycosmisic acid is a natural product from Nauclea officinalis. |
| T6943 |
Picropodophyllin |
Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expressio...
|
| TN2071 |
Picropodopyllotoxone |
Picropodopyllotoxone is a natural product |
| T8188 |
Podophyllotoxone |
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro. |
| TN2250 |
Syringaresinol |
(-)-Syringaresinol may be a potential chemotherapeutic agent for the treatment of cancer; it against H/R-induced cardiomyocyte injury and death, the degradation...
|
| TN2080 |
Pinoresinol |
Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitri...
|
| T3S1089 |
Phillygenin |
1. Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values. |
| T4S1545 |
(-)-Licarin B |
1.(-)-Licarin B has anti-mycobacterial activity. |
| TN1614 |
Episyringaresinol |
Episyringaresinol is a natural product from Kalimeris indica. |
| TN2334 |
Hydnocarpin |
Hydnocarpin (Hy) is a flavonoid isolated and purified from the seeds of Hydnocarpus wightiana Blume., and exhibits moderate cytotoxic on cancer cells |
| TN1816 |
Kadsurin |
Kadsurin has anti-oxidant activity, it induces enzymes capable of scavenging oxygen radical species in the liver. Kadsurin may be valuable antitumor promoters o...
|
| TN2084 |
Piperitol |
Piperitol has in vitro antioxidant potential, it also exhibits a stronger CNS depressant effect than that of M. rotundifolia. |
| T3836 |
Eudesmin |
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65...
|
| T5S2283 |
Sesamolin |
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 a...
|
| TN1038 |
Galgravin |
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloi...
|
| TN1782 |
Isolariciresinol |
Isolariciresinol has antioxidant and anti-inflammatory activities during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE). |
| TN1874 |
Liriodendrin |
Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities, it plays protective role in sepsis-induced acute lung injury, it regulates lung in...
|
| TN1916 |
Matairesinol |
Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-induci...
|
| T6S1917 |
Gomisin A |
1. Gomisin A may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPK...
|
| T6S1918 |
Schisantherin B |
1. Schisantherin B shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| TN1036 |
Gomisin D |
Gomisin D is a natural product |
| TN1072 |
Lappaol A |
Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also...
|
| TQ0217 |
Gomisin G |
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9. |
| TN2198 |
Secoisolariciresinol monoglucoside |
Secoisolariciresinol monoglucoside is a natural product from Linum usitatissimum L. |
| T6S0535 |
Pinoresinol diglucoside |
1. Pinoresinol diglucoside is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound. |
| TN2186 |
Schisantherin D |
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110. |
| TN2185 |
Schisantherin C |
Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| TN1707 |
Gomisin H |
Gomisin H is a natural product from Schizandra chinensis. |
| TN1018 |
Angeloylgomisin H |
Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines. |
| TN2272 |
Tigloylgomisin H |
Tigloylgomisin H represents a potential liver cancer prevention agent, it can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarc...
|
| TN1581 |
Dihydroguaiaretic acid |
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress. |
| T3S0488 |
Syringaresinol-di-O-glucoside |
1. Syringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure ...
|
| TN2273 |
Tigloylgomisin P |
Tigloylgomisin P shows moderate to marginal cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines. |
| T8297 |
Gomisin N |
Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy a...
|
| T6S1930 |
Schisanhenol |
1. Schisanhenol can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be th...
|
| TN1390 |
Angeloylgomisin Q |
Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL. |
| TN1706 |
Gomisin E |
Gomisin E is a natural product from Schizandra chinensis. |
| TN1709 |
Gomisin O |
Gomisin O is a natural product from Schizandra chinensis. |
| TN1609 |
Epigomisin O |
Epigomisin O is a natural product from Schizandra chinensis. |
| TN1351 |
9-O-Acetyl-4,4'-di-O-methyllariciresinol |
9-O-Acetyl-4,4'-di-O-methyllariciresinol is a natural product |
| TN1355 |
Acanthoside B |
Acanthoside has inhibitory effects on the allergic inflammation. |
| TN2090 |
Podophyllol |
Podophyllol is a natural product |
| TN1485 |
Chicanine |
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways. |
| TN2079 |
(-)-Pinoresinol |
Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulat...
|
| TN2241 |
Styraxlignolide F |
Styraxlignolide F is a natural product from Styrax japonica. |
| TN1708 |
Gomisin M2 |
Gomisin M2 is an anti-HIV agent. |
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