香豆素

香豆素(Coumarin)是在许多植物中发现的苯并吡喃类有机化合物中的一类化合物,具有多种生物学特性,包括抗菌、抗病毒、抗炎、抗糖尿病、抗氧化和酶抑制活性。

香豆素
产品编号 产品名称
TN1001 Apiosylskimmin Apiosylskimmin is a natural product from Angelica gigas.
T5744 Nsc267697 Nsc267697 is a natural product from Heracleum dissectum,and possess preventive and therapeutic effects on breast cancer but they have also cytotoxic effects on ...
TN1786 Isomeranzin Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
TN1415 Auraptenol Auraptenol possesses robust antidepressant-like efficacy in mice.
TN1557 Decursinol angelate Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of t...
T5776 pimpinellin Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
T5S1408 (+)-Pteryxin (+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
TN1516 Cnidicin Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 m...
TN1048 Cnidilin Cnidilin has high BBB permeability and has pharmacokinetic potentials for the treatment of central nervous system diseases.
TN1913 Marmin Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and se...
TN1345 8-Hydroxybergapten 8-Hydroxybergapten may have anti-wrinkle activity.
TN1243 3-Aminocoumarin 3-Aminocoumarin is a natural product
TN1388 Angelol K Angelol K shows significant activity on human platelet aggregation.
TN1391 Angenomalin Angenomalin is a natural product
TN1640 Fabiatrin Fabiatrin is a natural product
TJS0311 Ethyl coumarin-3-carboxylate
T3399 Psoralidin Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive ...
T3801 Byakangelicin Byakangelicin is an antineoplastic agent.
TN1386 Angelol A Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TN1046 Murrayone Murrayone can significantly inhibit the abnormal increase of platelet aggregation induced by ADP.
TN1069 Medicagol Medicagol is a natural product has the activity of estrogen
T4S1659 Xanthotoxol Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neur...
TN1905 Magnolioside Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a mode...
T4S1335 Daphnoretin 1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcom...
TJS0314 4-Methyllimetol 5,7-Dihydroxy-4-methylcoumarin inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiag...
TJS0315 7,8-Dihydroxy-4-methylcoumarin 1. 4-Methyldaphnetin is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radica...
T5774 7-demethylsuberosin 7-demethylsuberosin is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 produc...
TN1587 Dihydroseselin Dihydroseselin type of pyranocoumarin possessing a 4'-isovaleryl group is important to suksdorfin's enhanced anti-HIV activity.
TN1982 Neoglycyrol Neoglycyrol shows some cardioprotective effects .
T4946 COLUMBIANETIN ACETATE Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of columbianetin acetate is a passive diffusion pro...
T8169 Decursinol Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.
TJS0318 6-Hydroxy-4-methylcoumarin Growth inhibition of human U937 cells by [3H]thymidine incorporation assay
TN1015 Meranzin Meranzin exhibits strong anti-inflammatory and analgesic activity.
TN1552 Daphnetin dimethyl ether Daphnetin dimethyl ether is a product from Wikstroemia indica (Linn.) C. A. Mey.
T7934 7-Methylcoumarin 7-Methylcoumarin with strong hepatoprotective activity.
T3927 Phellopterin Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration ...
T6S0077 Byakangelicol 1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; ...
T6S0078 Oxypeucedanin hydrate 1. Oxypeucedanin hydrate has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabo...
T1548 8-Methoxypsoralen Methoxsalen is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methox...
T7970 7-Ethoxycoumarin 7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1.
TN1730 Heraclenol Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and he...
TN2041 Pangelin Pangelin is a natural product
T5742 Isodemethylwedelolacton Isodemethylwedelolacton is a natual product,has Clotting activity.
TN2024 Oxyimperatorin Oxyimperatorin is a natural product from Angelica dahurica.
T5S1286 Columbianetin Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. Columbiane...
TN1529 Coumarin VI Coumarin VI is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.
TQ0295 Coumestrol Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, can...
T4593 ISOPIMPINELLIN Antiviral, anti HIV.
T5747 ISOBERGAPTEN ISOBERGAPTEN is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum m...
TJS0856 Dalbergin 1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis...
T5758 sphondin Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level o...
T4S0592 Toddalolactone anti-inflammatory and analgesic.
TN1463 Calycanthoside Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity.
TN1120 Osthenol Osthenol shows antitumor-promoting activity, it also has antifungal and antibacterial activities.
T5S0045 Isofraxidin 1. Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protect...
T2S1434 Bergaptol 1. Bergaptol shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
TN1380 Ammijin Standard reference
T3872 Nodakenin Nodakenin is a compound with anti-allergic and anti-inflammatory activities.
T5S1413 Nodakenetin 1. Nodakenetin has clinical efficacy.
TN2098 (-)-Praeruptorin B (-)-Praeruptorin B is a natural product from Peucedanum praeruptorum Dunn.
T3384 Wedelolactone Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.
T3783 Fraxin Fraxin is a glucoside of fraxetin.
TJS0338 4-Methylesculetin 4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
T3888 Scopolin Scopolin formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesi...
T7049 Herniarin Herniarin is a natural coumarin with antitumor effect.
TJS0341 7-Amino-4-(trifluoromethyl)coumarin 7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2...
TN2316 Xanthyletin Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
TN2189 Scopoletin acetate Scopoletin acetate is a natural product
T5795 Suberosin Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as m...
TN1922 Meranzin hydrate Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-...
T3S1416 Decursin 1. Decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects ,...
T8211 3',4'-dihydro-3'-hydroxy-Xanthyletin 3',4'-dihydro-3'-hydroxy-Xanthyletin is a natural product from Angelica gigas.
T4S2354 Dimethylfraxetin Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
T2S0357 6-Hydroxycoumarin 6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a ...
T8113 4-Methyl-6-Methoxycoumarin 4-Methyl-6-Methoxycoumarin is a natural product isolated from Eupatorium pauciflorum.
TN1369 Alloimperatorin Alloimperatorin exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition o...
TN1703 Glycyrin Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
T7993 8-Acetyl-7-Hydroxycoumarin 8-Acetyl-7-Hydroxycoumarin is a natural compound,with Antifungal and antibacterial activities
TN2021 Osthol hydrate Osthol hydrate is a natural product
TN2330 Caffeic Acid 3-Methyl Phenethyl Ester Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane indu...
T6S1418 Praeruptorin C 1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by i...
T4S1419 Praeruptorin A 1. Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Prae...
T3777 Praeruptorin A Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2...
T4S1421 Praeruptorin D Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via ...
T3S0081 Oxypeucedanin 1. Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeuc...
T5S0669 Bergamotine 1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A<sup>y</sup>diabetic mice.
TN1343 8-Geranyloxypsoralen 8-Geranyloxypsoralen inhibits α²-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat a...
TWS1613 mulberroside B Antitussive, antiasthmatic, hypoglycemic, anti - tumor, treatment of gout.
TN1511 Cleomiscosin A Cleomiscosin A has antioxidant activity, it could be beneficial in preventing LDL oxidation in atherosclerotic lesions, it shows inhibitory activity to TNF-α±...
T5070 5,7-Dihydroxy-4-phenylcoumarin 5,7-dihydroxy-4-phenyl coumarin is found in the plant Passiflora serratodigitata with the antibacterial activity.
T3815 Isoscopoletin 6-Hydroxy-7-methoxycoumarin is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
T4S1422 Praeruptorin E 1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those...
T6S1423 Praeruptorin B 1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.
TN1387 Angelol B The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TJS0368 7,8-Dihydroxy-4-phenylcoumarin 7,8-Dihydroxy-4-phenylcoumarin inhibits the activity of Staphylococcus aureus DNA helicase
THS1455 DihydroarteMisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to...
T8038 7-Ethoxy-4-Methylcoumarin 7-Ethoxy-4-Methylcoumarin is a natural organic compound
TN2214 Smyrindioloside Smyrindioloside is a natural product from Smyrnopsis aucheri Karjag.
T6S1435 Notopterol 1. Notopterol induces apoptosis and inhibits cell cycle-specific.
T1391 4-Methylumbelliferone Hymecromone is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECH...
Apiosylskimmin
TN1001CAS 103529-94-8
Apiosylskimmin is a natural product from Angelica gigas.
Nsc267697
T5744CAS 10387-50-5
Nsc267697 is a natural product from Heracleum dissectum,and possess preventive and therapeutic effects on breast cancer but they have also cytotoxic effects on ...
Isomeranzin
TN1786CAS 1088-17-1
Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
Auraptenol
TN1415CAS 1221-43-8
Auraptenol possesses robust antidepressant-like efficacy in mice.
Decursinol angelate
TN1557CAS 130848-06-5
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of t...
pimpinellin
T5776CAS 131-12-4
Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
(+)-Pteryxin
T5S1408CAS 13161-75-6
(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
Cnidicin
TN1516CAS 14348-21-1
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 m...
Cnidilin
TN1048CAS 14348-22-2
Cnidilin has high BBB permeability and has pharmacokinetic potentials for the treatment of central nervous system diseases.
Marmin
TN1913CAS 14957-38-1
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and se...
8-Hydroxybergapten
TN1345CAS 1603-47-0
8-Hydroxybergapten may have anti-wrinkle activity.
3-Aminocoumarin
TN1243CAS 1635-31-0
3-Aminocoumarin is a natural product
Angelol K
TN1388CAS 169736-93-0
Angelol K shows significant activity on human platelet aggregation.
Angenomalin
TN1391CAS 18199-64-9
Angenomalin is a natural product
Fabiatrin
TN1640CAS 18309-73-4
Fabiatrin is a natural product
Ethyl coumarin-3-carboxylate
TJS0311CAS 1846-76-0
Psoralidin
T3399CAS 18642-23-4
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive ...
Byakangelicin
T3801CAS 19573-01-4
Byakangelicin is an antineoplastic agent.
Angelol A
TN1386CAS 19625-17-3
Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
Murrayone
TN1046CAS 19668-69-0
Murrayone can significantly inhibit the abnormal increase of platelet aggregation induced by ADP.
Medicagol
TN1069CAS 1983-72-8
Medicagol is a natural product has the activity of estrogen
Xanthotoxol
T4S1659CAS 2009-24-7
Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neur...
Magnolioside
TN1905CAS 20186-29-2
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a mode...
Daphnoretin
T4S1335CAS 2034-69-7
1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcom...
4-Methyllimetol
TJS0314CAS 2107-76-8
5,7-Dihydroxy-4-methylcoumarin inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiag...
7,8-Dihydroxy-4-methylcoumarin
TJS0315CAS 2107-77-9
1. 4-Methyldaphnetin is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radica...
7-demethylsuberosin
T5774CAS 21422-04-8
7-demethylsuberosin is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 produc...
Dihydroseselin
TN1587CAS 2221-66-1
Dihydroseselin type of pyranocoumarin possessing a 4'-isovaleryl group is important to suksdorfin's enhanced anti-HIV activity.
Neoglycyrol
TN1982CAS 23013-84-5
Neoglycyrol shows some cardioprotective effects .
COLUMBIANETIN ACETATE
T4946CAS 23180-65-6
Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of columbianetin acetate is a passive diffusion pro...
Decursinol
T8169CAS 23458-02-8
Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.
6-Hydroxy-4-methylcoumarin
TJS0318CAS 2373-31-1
Growth inhibition of human U937 cells by [3H]thymidine incorporation assay
Meranzin
TN1015CAS 23971-42-8
Meranzin exhibits strong anti-inflammatory and analgesic activity.
Daphnetin dimethyl ether
TN1552CAS 2445-80-9
Daphnetin dimethyl ether is a product from Wikstroemia indica (Linn.) C. A. Mey.
7-Methylcoumarin
T7934CAS 2445-83-2
7-Methylcoumarin with strong hepatoprotective activity.
Phellopterin
T3927CAS 2543-94-4
Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration ...
Byakangelicol
T6S0077CAS 26091-79-2
1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; ...
Oxypeucedanin hydrate
T6S0078CAS 2643-85-8
1. Oxypeucedanin hydrate has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabo...
8-Methoxypsoralen
T1548CAS 298-81-7
Methoxsalen is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methox...
7-Ethoxycoumarin
T7970CAS 31005-02-4
7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1.
Heraclenol
TN1730CAS 31575-93-6
Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and he...
Pangelin
TN2041CAS 33783-80-1
Pangelin is a natural product
Isodemethylwedelolacton
T5742CAS 350681-33-3
Isodemethylwedelolacton is a natual product,has Clotting activity.
Oxyimperatorin
TN2024CAS 35740-18-2
Oxyimperatorin is a natural product from Angelica dahurica.
Columbianetin
T5S1286CAS 3804-70-4
Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. Columbiane...
Coumarin VI
TN1529CAS 38215-36-0
Coumarin VI is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.
Coumestrol
TQ0295CAS 479-13-0
Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, can...
ISOPIMPINELLIN
T4593CAS 482-27-9
Antiviral, anti HIV.
ISOBERGAPTEN
T5747CAS 482-48-4
ISOBERGAPTEN is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum m...
Dalbergin
TJS0856CAS 482-83-7
1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis...
sphondin
T5758CAS 483-66-9
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level o...
Toddalolactone
T4S0592CAS 483-90-9
anti-inflammatory and analgesic.
Calycanthoside
TN1463CAS 483-91-0
Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity.
Osthenol
TN1120CAS 484-14-0
Osthenol shows antitumor-promoting activity, it also has antifungal and antibacterial activities.
Isofraxidin
T5S0045CAS 486-21-5
1. Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protect...
Bergaptol
T2S1434CAS 486-60-2
1. Bergaptol shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
Ammijin
TN1380CAS 495-30-7
Standard reference
Nodakenin
T3872CAS 495-31-8
Nodakenin is a compound with anti-allergic and anti-inflammatory activities.
Nodakenetin
T5S1413CAS 495-32-9
1. Nodakenetin has clinical efficacy.
(-)-Praeruptorin B
TN2098CAS 4970-26-7
(-)-Praeruptorin B is a natural product from Peucedanum praeruptorum Dunn.
Wedelolactone
T3384CAS 524-12-9
Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.
Fraxin
T3783CAS 524-30-1
Fraxin is a glucoside of fraxetin.
4-Methylesculetin
TJS0338CAS 529-84-0
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
Scopolin
T3888CAS 531-44-2
Scopolin formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesi...
Herniarin
T7049CAS 531-59-9
Herniarin is a natural coumarin with antitumor effect.
7-Amino-4-(trifluoromethyl)coumarin
TJS0341CAS 53518-15-3
7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2...
Xanthyletin
TN2316CAS 553-19-5
Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
Scopoletin acetate
TN2189CAS 56795-51-8
Scopoletin acetate is a natural product
Suberosin
T5795CAS 581-31-7
Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as m...
Meranzin hydrate
TN1922CAS 5875-49-0
Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-...
Decursin
T3S1416CAS 5928-25-6
1. Decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects ,...
3',4'-dihydro-3'-hydroxy-Xanthyletin
T8211CAS 5993-18-0
3',4'-dihydro-3'-hydroxy-Xanthyletin is a natural product from Angelica gigas.
Dimethylfraxetin
T4S2354CAS 6035-49-0
Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
6-Hydroxycoumarin
T2S0357CAS 6093-68-1
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a ...
4-Methyl-6-Methoxycoumarin
T8113CAS 6295-35-8
4-Methyl-6-Methoxycoumarin is a natural product isolated from Eupatorium pauciflorum.
Alloimperatorin
TN1369CAS 642-05-7
Alloimperatorin exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition o...
Glycyrin
TN1703CAS 66056-18-6
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
8-Acetyl-7-Hydroxycoumarin
T7993CAS 6748-68-1
8-Acetyl-7-Hydroxycoumarin is a natural compound,with Antifungal and antibacterial activities
Osthol hydrate
TN2021CAS 69219-24-5
Osthol hydrate is a natural product
Caffeic Acid 3-Methyl Phenethyl Ester
TN2330CAS 71835-85-3
Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane indu...
Praeruptorin C
T6S1418CAS 72463-77-5
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by i...
Praeruptorin A
T4S1419CAS 73069-25-7
1. Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Prae...
Praeruptorin A
T3777CAS 73069-27-9
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2...
Praeruptorin D
T4S1421CAS 73069-28-0
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via ...
Oxypeucedanin
T3S0081CAS 737-52-0
1. Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeuc...
Bergamotine
T5S0669CAS 7380-40-7
1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A<sup>y</sup>diabetic mice.
8-Geranyloxypsoralen
TN1343CAS 7437-55-0
8-Geranyloxypsoralen inhibits α²-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat a...
mulberroside B
TWS1613CAS 75872-12-7
Antitussive, antiasthmatic, hypoglycemic, anti - tumor, treatment of gout.
Cleomiscosin A
TN1511CAS 76948-72-6
Cleomiscosin A has antioxidant activity, it could be beneficial in preventing LDL oxidation in atherosclerotic lesions, it shows inhibitory activity to TNF-α±...
5,7-Dihydroxy-4-phenylcoumarin
T5070CAS 7758-73-8
5,7-dihydroxy-4-phenyl coumarin is found in the plant Passiflora serratodigitata with the antibacterial activity.
Isoscopoletin
T3815CAS 776-86-3
6-Hydroxy-7-methoxycoumarin is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
Praeruptorin E
T4S1422CAS 78478-28-1
1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those...
Praeruptorin B
T6S1423CAS 81740-07-0
1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.
Angelol B
TN1387CAS 83156-04-1
The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
7,8-Dihydroxy-4-phenylcoumarin
TJS0368CAS 842-01-3
7,8-Dihydroxy-4-phenylcoumarin inhibits the activity of Staphylococcus aureus DNA helicase
DihydroarteMisinic acid
THS1455CAS 85031-59-0
Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to...
7-Ethoxy-4-Methylcoumarin
T8038CAS 87-05-8
7-Ethoxy-4-Methylcoumarin is a natural organic compound
Smyrindioloside
TN2214CAS 87592-77-6
Smyrindioloside is a natural product from Smyrnopsis aucheri Karjag.
Notopterol
T6S1435CAS 88206-46-6
1. Notopterol induces apoptosis and inhibits cell cycle-specific.
4-Methylumbelliferone
T1391CAS 90-33-5
Hymecromone is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECH...
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