TN1266
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3-O-Methylquercetin
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3-O-Methylquercetin 是分离自植物Rhamnus nakaharai的天然产物,可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。
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T3929
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Kaurenoic acid
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Kaurenoic acid 是一种二萜,来源于Sphagneticola trilobata中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。
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TN1643
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Ferulamide
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Ferulamide 是从巴豆中分离的阿魏酸衍生物,具有抗胆碱酯酶活性。
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T6S0033
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Crotonoside
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2-Hydroxyadenosine 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。
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TN2974
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3-O-Methylquercetin tetraacetate
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Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness.
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TN3945
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ent-3-Oxokauran-17-oic acid
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TN4392
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Koaburaside
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Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.
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TN4393
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Koaburaside monomethyl ether
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Standard reference
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T5136
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Kongensin A
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Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
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TN3943
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ent-17-Hydroxykauran-3-one
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ent-17-Hydroxy-16α-kauran-3-one shows weak antimicrobial activity when tested against Staphylococcusaureus.
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TN3946
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ent-3-Oxokaurane-16,17-diol
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AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
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TN3959
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ent-kaurane-3,16,17-triol
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Kaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan- 3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
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