干细胞分化化合物库

Stem cell Differentiation Compound Library
产品编号 L8000
  库化合物信息   Excel SDF

干细胞具有分化成特定细胞亚型的能力,例如,胚胎干细胞可以产生所有三个胚层的细胞:外胚层、中胚层和内胚层。通常认为成体干细胞效力有限,只能分化成某些细胞类型。为了产生用于再生医学、药物筛选、疾病或发育模型相关的特化细胞类型,研究人员必须控制和指导干细胞的分化。细胞的分化方向可以通过天然或化学合成的小分子来诱导。例如,糖原合成酶激酶-3β的特异性抑制剂可以诱导多能干细胞中的神经元分化,特定细胞因子和组蛋白去乙酰化酶抑制剂丁酸钠的组合诱导干细胞分化成肝细胞等。

TargetMol干细胞分化化合物库是1014种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,为干细胞相关研究提供有效工具。

干细胞分化化合物库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 133868.00
250 μL * 10 mM (in DMSO) 222980.00
1 mg 222980.00
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产品描述

  • 1014种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
  • 研究干细胞再生机理、再生疗法; 用于干细胞分化信号通路的研究以及基于干细胞的新药物筛选的有效工具;
  • 靶点含Wnt、 GSK-3、Hedgehog、JAK、ROCK、γ-secretase等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书、化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L8000)

化合物库组成

PI3K (110)
JAK (63)
PPAR (61)
mTOR (58)
Histone Methyltransferase (51)
p38 MAPK (46)
STAT (44)
Wnt/beta-catenin (40)
Akt (40)
CDK (36)
GSK-3 (33)
AMPK (32)
TGF-beta/Smad (29)
ERK (28)
DNA-PK (26)
EGFR (25)
ALK (23)
S6 Kinase (23)
Src (22)
Tyrosine Kinases (22)
PKC (22)
p53 (21)
Histone Demethylase (21)
Casein Kinase (20)
ATM/ATR (20)
VEGFR (20)
Hedgehog/Smoothened (19)
NF-κB (19)
Gamma-secretase (18)
ROCK (18)
PKA (17)
MEK (14)
FLT (13)
DNA Methyltransferase (13)
Aurora Kinase (12)
Mdm2 (12)
Raf (12)
Sirtuin (11)
Autophagy (11)
CXCR (11)
Bcr-Abl (10)
ATPase (9)
Adrenergic Receptor (9)
c-Kit (9)
COX (9)
JNK (9)
HDAC (9)
PDE (9)
PDK (9)
PDGFR (8)
Potassium Channel (8)
P450 (8)
Histone Acetyltransferase (8)
FGFR (8)
Endogenous Metabolite (8)
Beta Amyloid (8)
Epigenetic Reader Domain (7)
TNF (7)
Retinoid Receptor (6)
c-RET (6)
c-Met/HGFR (6)
DNA/RNA Synthesis (6)
5-HT Receptor (6)
Apoptosis (6)
IGF-1R (6)
MAPK (6)
Histamine Receptor (5)
MMP (5)
Porcupine (5)
AChR (5)
Dehydrogenase (5)
Chk (5)
Carbonic Anhydrase (5)
Sodium Channel (5)
Syk (5)
Trk receptor (4)
Estrogen/progestogen Receptor (4)
Pim (4)
OCT (4)
PARP (4)
IL Receptor (4)
IκB/IKK (3)
MAO (3)
LRRK2 (3)
HER (3)
Mitochondrial Metabolism (3)
Dopamine Receptor (3)
GABA Receptor (3)
Glucokinase (3)
c-Myc (3)
BTK (3)
Caspase (3)
c-Fms (3)
Antioxidant (3)
BCL (3)
Vitamin (3)
SGK (3)
PTEN (3)
Rho (3)
ROS (3)
Serine Protease (3)
Serine/threonin kinase (2)
S1P Receptor (2)
SIK (2)
Smo (2)
Tyrosinase (2)
transporter (2)
AhR (2)
BACE (2)
Calcium Channel (2)
ABC (2)
Apoptosis inducer (2)
Antibiotic (2)
cholecystokinin (2)
Cysteine Protease (2)
GR (2)
Glucocorticoid Receptor (2)
Fatty Acid Synthase (2)
MLK (2)
NADPH (2)
PI4K (2)
Phosphatase (2)
HIF (2)
Hippo pathway (2)
Hck (2)
HSP (2)
Microtubule Associated (2)
Lipoxygenase (2)
Immunology & Inflammation related (1)
Integrin (1)
MELK (1)
lysosomal autophagy (1)
HSV (1)
Hydroxylase (1)
HIV Protease (1)
Histone Acetylation (1)
hCE (1)
Phospholipase (1)
Phosphorylase (1)
P-gp (1)
PLK (1)
Prostaglandin Receptor (1)
Proteasome (1)
NADPH-oxidase (1)
NAMPT (1)
MNK (1)
MRP (1)
PAI-1 (1)
NMDAR (1)
Nrf2 (1)
DUB (1)
DYRK (1)
E1/E2/E3 Enzyme (1)
GRK (1)
GluR (1)
GPR (1)
DHFR (1)
DNA (1)
DNA Alkylation (1)
DNA Alkylator/Crosslinker (1)
Chloride channel (1)
CSF-1R (1)
Antifection (1)
Antifungal (1)
Antibacterial (1)
Arginase (1)
Aromatase (1)
ACK (1)
Adenosine Receptor (1)
advanced glycation end products (1)
Amino Acids and Derivatives (1)
BMI-1 (1)
Antiviral (1)
UGT (1)
VDA (1)
Wnk (1)
YAP (1)
TACC (1)
TAM Receptor (1)
Stemness kinase (1)
Topoisomerase (1)
Tie-2 (1)
Sigma receptor (1)
Salt-Inducible Kinase (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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