神经递质受体化合物库

Neurotransmitter Receptor Compound Library
产品编号 L2610
  库化合物信息   Excel SDF

神经递质是人类行为的化学基础。研究证实行为病理大都由一个或数个神经递质缺失或增多失平衡引起。躯体疾病也可由于特殊的神经径路障碍引起,例如帕金森病(PD)。脑内神经递质分为生物原胺类、氨基酸类、肽类、乙酰胆碱类等。生物原胺类神经递质包括:多巴胺(DA)、去甲肾上腺素(NE)、肾上腺素(E)、5-羟色胺(5-HT)也称(血清素)。氨基酸类神经递质包括:γ-氨基丁酸(GABA)、甘氨酸、谷氨酸、组胺。肽类神经递质分为:内源性阿片肽、P物质、神经加压素、胆囊收缩素(CCK)、生长抑素、血管加压素和缩宫素、神经肽Y。其它神经递质还有:核苷酸类、花生酸碱、阿南德酰胺、sigma受体(σ受体)。在突触后膜或效应器细胞膜上有能与神经递质相结合的特殊蛋白质,称神经递质受体或突触后受体。许多精神药物作用于神经递质受体。

TargetMol收集了1290种神经递质受体相关的化合物,可用于神经系统药物的开发。

神经递质受体化合物库
规格 价格/RMB
30 μL * 10 mM (in DMSO) 80700.00
100 μL * 10 mM (in DMSO) 185900.00
250 μL * 10 mM (in DMSO) 278000.00
1 mg 278000.00
咨询化合物库

产品描述

  • 1290种与神经递质受体相关的化合物,用于高通量、高内涵筛选;
  • 靶点包括5-HT receptor、AChR、GABA receptor、dopamine receptor、Opiod receptor等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2610)

化合物库组成

AChR (222)
5-HT Receptor (202)
Adrenergic Receptor (160)
Dopamine Receptor (126)
Histamine Receptor (86)
GABA Receptor (80)
GluR (63)
Opioid Receptor (50)
NMDAR (41)
Adenosine Receptor (24)
Norepinephrine (23)
Potassium Channel (15)
Sigma receptor (15)
Sodium Channel (11)
PDE (9)
Calcium Channel (9)
Monoamine Transporter (6)
HDAC (5)
iGluR (4)
P450 (4)
CaMK (4)
BACE (4)
Tyrosinase (4)
TNF (3)
Serotonin Transporter (3)
TRP/TRPV Channel (3)
Dehydrogenase (3)
Chloride channel (3)
Phospholipase (3)
DNA/RNA Synthesis (3)
MMP (2)
LDL (2)
GlyT (2)
Autophagy (2)
Beta Amyloid (2)
EGFR (2)
Endogenous Metabolite (2)
Adiponectin receptor (2)
ABC (2)
Androgen Receptor (2)
Antibacterial (2)
Antifection (2)
VEGFR (2)
Transferase (1)
Syk (1)
TGF-beta/Smad (1)
PPAR (1)
Prostaglandin Receptor (1)
PTP1B (1)
Antifolate (1)
ATPase (1)
Aurora Kinase (1)
AChE (1)
BCL (1)
Bcr-Abl (1)
Amino Acids and Derivatives (1)
Cannabinoid Receptor (1)
Carbonic Anhydrase (1)
Caspase (1)
CAT (1)
CCR (1)
ERK (1)
Estrogen/progestogen Receptor (1)
FAK (1)
Gap Junction Protein (1)
GluCls (1)
Glucocorticoid Receptor (1)
Glucokinase (1)
COX (1)
DNA Alkylation (1)
DNA Methyltransferase (1)
DYRK (1)
GPR (1)
GRK (1)
GSK-3 (1)
GST (1)
HCV Protease (1)
HER (1)
Histone Methyltransferase (1)
HIV Protease (1)
lysosomal autophagy (1)
MEK (1)
IL Receptor (1)
Integrin (1)
MRP (1)
MT Receptor (1)
mTOR (1)
NADPH (1)
NF-κB (1)
NOD (1)
P2 Receptor (1)
PI3K (1)
PKA (1)
PKM (1)
Platelet aggregation (1)
PAFR (1)
Parasite (1)
PARP (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
陶术生物的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务,也不为任何个人提供产品和服务。陶素|陶素生化|陶术|陶术生物
微信公众号
Copyright © 2018 Topscience Co. Ltd. All rights reserved. 沪ICP备20019793号-2 沪公网安备 31010602004043号