离子通道库

Ion Channel Inhibitor Library
产品编号 L2300
  库化合物信息   Excel SDF

离子跨膜通道的调节是治疗多种疾病的基础,离子通道是开发新的高效药物治疗的重要靶点,随着人类基因组计划的完成和转录机制研究的深入,离子通道分布的组织特异性逐渐得以阐明,这将使离子通道成为一类有选择性的组织特异性药物靶点。离子通道对于细胞间通讯至关重要,并调节多种重要的生理过程,这些过程功能障碍,可导致广泛的疾病和病理状况,如糖尿病、神经性疼痛、心血管疾病、大脑和外周血管疾病、哮喘、神经退行性疾病。

为满足客户离子通道相关研究的化合物需求,我们根据文献报道和其他公开资料精心整理946种与离子通道相关的生物活性小分子化合物,适用于离子通道相关的疾病和药物研究。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
离子通道库
规格
30 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
1 mg
咨询化合物库

产品描述

  • 946种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选;
  • 靶点含K+通道、Ca2+通道、Na+通道、质子泵等;
  • 通过前期临床研究和临床实验,生物活性和安全性已经得到验证;
  • 其中一些活性化合物已得到FDA批准上市;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR和HPLC检测技术保证产品高纯度和高质量;
  • 所有化合物现货供应。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2300)

化合物库组成

Potassium Channel (99)
Calcium Channel (84)
GABA Receptor (78)
Sodium Channel (78)
TRP/TRPV Channel (60)
AChR (43)
ATPase (38)
NMDAR (24)
Chloride channel (18)
COX (16)
GluR (15)
5-HT Receptor (15)
Adrenergic Receptor (15)
CFTR (13)
P-gp (12)
P450 (11)
SGLT (11)
Proton pump (11)
Dopamine Receptor (11)
ABC (10)
EGFR (8)
P2 Receptor (8)
Histamine Receptor (7)
Carbonic Anhydrase (7)
CaMK (6)
Monoamine Transporter (6)
Monocarboxylate transporter (6)
IL Receptor (5)
NF-κB (5)
Endogenous Metabolite (5)
TNF (5)
GPR (4)
HER (4)
AMPK (4)
NPC1L1 (4)
OCT (4)
iGluR (4)
MRP (4)
PPAR (4)
PKC (4)
PDE (3)
PKA (3)
Platelet aggregation (3)
MMP (3)
Opioid Receptor (3)
NADPH (3)
Na-K-Cl cotransporter (3)
Antibacterial (3)
HIV Protease (3)
HMG-CoA Reductase (3)
Integrin (3)
CRM1 (3)
VDAC (3)
transporter (3)
VEGFR (2)
Estrogen/progestogen Receptor (2)
GlyT (2)
HIF (2)
Glucocorticoid Receptor (2)
Hedgehog/Smoothened (2)
AhR (2)
Cannabinoid Receptor (2)
BCRP (2)
Autophagy (2)
BCL (2)
Antifection (2)
Apoptosis (2)
Norepinephrine (2)
NOS (2)
LDL (2)
Lipid (2)
Lipoxygenase (2)
mTOR (2)
Syk (2)
ROS (2)
OAT (2)
Phospholipase (2)
PKM (1)
Prostaglandin Receptor (1)
Protease-activated Receptor (1)
PDK (1)
Phosphatase (1)
p97 (1)
PAI-1 (1)
Parasite (1)
PARP (1)
S1P Receptor (1)
S6 Kinase (1)
Serine Protease (1)
Serine/threonin kinase (1)
RAAS (1)
Reductase (1)
ribosome (1)
ROCK (1)
TGF-beta/Smad (1)
Thrombin (1)
Src (1)
STAT (1)
Sigma receptor (1)
Myosin (1)
Na+/Ca2+ Exchanger (1)
N-Acetylglucosaminyltransferase (1)
MT Receptor (1)
MAO (1)
Microtubule Associated (1)
Mitochondrial Metabolism (1)
Influenza Virus (1)
NOD (1)
NKCC (1)
Nrf2 (1)
P2X Receptor (1)
p38 MAPK (1)
Apoptosis inducer (1)
Aquaporin (1)
Bcr-Abl (1)
Beta Amyloid (1)
Beta-Secretase (1)
Casein Kinase (1)
Caspase (1)
CGRP Receptor (1)
Akt (1)
Amino Acids and Derivatives (1)
ACAT (1)
AChE (1)
Antibiotic (1)
Adenosine Receptor (1)
Adiponectin receptor (1)
Androgen Receptor (1)
Anion Exchanger (1)
Annexin A (1)
GR (1)
GST (1)
HBV (1)
HCN Channel (1)
HDAC (1)
IP3 Receptor  (1)
IκB/IKK (1)
JNK (1)
IAP (1)
Gap Junction Protein (1)
GluCls (1)
FAAH (1)
ERK (1)
Dehydrogenase (1)
DNA gyrase (1)
DNA Methyltransferase (1)
DNA/RNA Synthesis (1)
DPP-4 (1)
c-Myc (1)
Wnt/beta-catenin (1)
Topoisomerase (1)
Transaminase (1)
Tyrosinase (1)
UGT (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat Fasiglifam TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS-754807 Enmetazobactam
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG-208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol TRIA-662 MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv 3-Pyridinemethanol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 BMP signaling agonist sb4 Daclatasvir Daclatasvir dihydrochloride NADPH tetracyclohexanamine AZD-8055 Vistusertib PAβN dihydrochloride HZ-1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin-3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A 78U Tenovin-6 Normetanephrine hydrochloride Triclocarban CUDC-101 Chlorpropham Pyridostigmine bromide Zacopride hydrochloride PF-04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine dihydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
陶术生物的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务,也不为任何个人提供产品和服务。陶素|陶素生化|陶术|陶术生物
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