抑制剂库

Inhibitor Library
产品编号 L2000
  库化合物信息   Excel SDF

细胞信号控制细胞基本活动,调控细胞行为。细胞感知并准确响应微环境的变化是发育、组织修复和免疫的基础,也是正常组织稳态的基础。细胞信号间相互作用异常或细胞信息处理错误是导致癌症、自身免疫和糖尿病等疾病的原因。深入了解细胞信号传导,疾病可得到更有效的治疗。

TargetMol抑制剂库是由5700个靶向小分子化合物组成的集合,每一个化合物都有明确的抑制靶点,靶点所处的信号通路也因此被阻断,TargetMol抑制剂库是研究信号通路及相关疾病的有力工具,可用于高通量筛选和高内涵筛选。

抑制剂库
规格 价格/RMB
30 μL * 10 mM (in DMSO) 171800.00
100 μL * 10 mM (in DMSO) 381900.00
250 μL * 10 mM (in DMSO) 666900.00
1 mg 666900.00
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产品描述

  • 5700个小分子抑制剂的独特集合,主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选;
  • 通过临床前研究和临床实验,生物活性和安全性已经得到验证;部分抑制剂已经被FDA批准上市;
  • 作用于MAPK、PI3K、JAK、HDAC、VEGFR、CDK等靶点,阻断相关信号通路;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2000)

化合物库组成

AChR (157)
COX (143)
5-HT Receptor (126)
PI3K (107)
CDK (102)
DNA/RNA Synthesis (97)
EGFR (91)
VEGFR (91)
Dopamine Receptor (89)
Adrenergic Receptor (88)
Dehydrogenase (78)
Histamine Receptor (74)
HDAC (73)
Sodium Channel (68)
PDE (67)
Epigenetic Reader Domain (65)
Calcium Channel (63)
JAK (63)
Src (62)
Potassium Channel (62)
PDGFR (57)
P450 (57)
NF-κB (56)
Histone Methyltransferase (55)
FGFR (55)
Estrogen/progestogen Receptor (54)
Bcr-Abl (54)
mTOR (54)
FLT (53)
HIV Protease (52)
Microtubule Associated (50)
Topoisomerase (50)
Raf (49)
Antibacterial (49)
TNF (47)
RAAS (46)
TRP/TRPV Channel (44)
GABA Receptor (44)
c-Kit (43)
PKC (42)
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Autophagy (41)
c-Met/HGFR (40)
Akt (39)
ALK (39)
GluR (38)
MAO (38)
ERK (37)
BCL (35)
GSK-3 (35)
STAT (35)
Wnt/beta-catenin (35)
PPAR (33)
HCV Protease (33)
ATPase (33)
Tyrosine Kinases (32)
Androgen Receptor (31)
Apoptosis (30)
Glucocorticoid Receptor (30)
DNA-PK (30)
PARP (30)
HSP (29)
MEK (29)
Antifection (29)
Aurora Kinase (29)
BTK (28)
Carbonic Anhydrase (28)
NMDAR (28)
Antibiotic (27)
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MMP (26)
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ROS (24)
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DNA Methyltransferase (13)
E1/E2/E3 Enzyme (12)
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AMPK (12)
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Stearoyl-CoA Desaturase (SCD) (1)
stilbene oxidase (1)
TACC (1)
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Thioredoxin (1)
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MALT (1)
Melatonin Receptor (1)
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IP3 Receptor  (1)
IRAK (1)
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LHRH (1)
Integrase (1)
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OCT (1)
NKCC (1)
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gp120/CD4 (1)
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FOXO1 (1)
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Anion Exchanger (1)
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APC (1)
Apelin receptor (1)
aconitase (1)
Adenylyl cyclase (1)
Bombesin Receptor (1)
CGRP Receptor (1)
Cell wall (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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