The fragment selection has been made with an emphasis on the high structural quality of molecules and easy performance and interpretation of 19F NMR screening results. Fluorinated Fragments Library contains 1000 compounds.
|100 μL * 10 mM (in DMSO)||待询|
|250 μL * 10 mM (in DMSO)||待询|
Enamine holds expertise in organofluorine chemistry with over 50 scientific papers in this research area published in the last 10 years. Our chemists are heavily involved in research on new synthetic methodologies for introducing fluorine atoms into a wide range of aliphatic/aromatic heterocyclic cores and various side chains. Very simple/trivial cores with overused chemistry; compounds having more than two stereocenters, showing rotamers, diastereoisomeric mixtures, as well as molecules prone to aggregation, have been removed from the set.