含氟片段库

Fluorinated Fragments Library
产品编号 EN4800
  库化合物信息   Excel SDF

The fragment selection has been made with an emphasis on the high structural quality of molecules and easy performance and interpretation of 19F NMR screening results. Fluorinated Fragments Library contains 1000 compounds.

含氟片段库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 待询
250 μL * 10 mM (in DMSO) 待询
1 mg 待询
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Enamine holds expertise in organofluorine chemistry with over 50 scientific papers in this research area published in the last 10 years. Our chemists are heavily involved in research on new synthetic methodologies for introducing fluorine atoms into a wide range of aliphatic/aromatic heterocyclic cores and various side chains. Very simple/trivial cores with overused chemistry; compounds having more than two stereocenters, showing rotamers, diastereoisomeric mixtures, as well as molecules prone to aggregation, have been removed from the set.

Key features

  • Experimentally confirmed solubilityin PBS buffer at 1 mM, in DMSO at 200 mM.
  • 19F NMR chemical shiftsare provided for all compounds in aqueous PBS or DMSO solutions.
  • Full Ro3 compliance, no reactive and unstable compounds, stability in DMSO solutionhas been tested.
  • 15200 in-stock analoguesare available (MW 160…400).
  • Cherry-picking is possible; delivery in any custom format including dry powders or DMSO solution in vials, microtubes or plates within 1–3 weeks.

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包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (EN4800)
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