DNA 损伤和修复分子库

DNA Damage & Repair Compound Library
产品编号 L3900
  库化合物信息   Excel SDF

癌细胞的耐药性是癌症治疗过程中面临的主要挑战,因此鉴定新的生物学靶标,并开发设计相应的药物成为重要策略,在各种潜在候选靶标中,癌细胞DNA Damage & Repair系统是重要的靶标。由于抗生素的滥用,细菌等微生物的耐药性越来越强,开发靶向微生物DNA Damage & Repair系统的药物迫在眉睫。

TargetMol DNA损伤和修复分子库是937个与DNA损伤和修复紧密相关的化合物集合,可用于DNA损伤和修复相关研究的高通量筛选,高内涵筛选。

DNA 损伤和修复分子库
规格 价格/RMB
30 μL * 10 mM (in DMSO) 59000.00
100 μL * 10 mM (in DMSO) 135800.00
250 μL * 10 mM (in DMSO) 201455.00
1 mg 201455.00
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产品描述

  • 937个与DNA损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体;
  • 涵盖与DNA损伤和修复相关的热门靶点,如HDAC、DNA/RNA Synthesis、Topoisomerase等;
  • 通过临床前研究和临床实验,生物活性和生物安全性得到保障;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L3900)

化合物库组成

DNA/RNA Synthesis (110)
HDAC (73)
PPAR (67)
Topoisomerase (57)
PARP (32)
CDK (32)
DNA-PK (30)
Sirtuin (28)
PI3K (26)
ATM/ATR (24)
DNA Alkylation (23)
Microtubule Associated (22)
mTOR (18)
Aurora Kinase (15)
Casein Kinase (14)
DNA gyrase (13)
Autophagy (10)
HSP (10)
Reverse Transcriptase (9)
ROCK (9)
Nucleoside Antimetabolite/Analog (9)
Bcr-Abl (9)
DHFR (9)
Wnt/beta-catenin (9)
COX (8)
Dehydrogenase (8)
AChR (8)
NF-κB (8)
GSK-3 (7)
Src (7)
Telomerase (7)
Endogenous Metabolite (6)
DUB (6)
Antifection (6)
HIV Protease (6)
P450 (6)
PERK (6)
PKA (6)
PKC (6)
PLK (6)
Potassium Channel (5)
PDGFR (5)
HSV (5)
Antibacterial (5)
BMI-1 (5)
DNA (5)
Epigenetic Reader Domain (5)
ERK (5)
TNF (5)
VEGFR (5)
Vitamin (4)
FLT (4)
GABA Receptor (4)
BCL (4)
ATPase (4)
Antiviral (4)
Apoptosis (4)
IL Receptor (4)
Kinesin (4)
LIM Kinase (4)
MEK (4)
p53 (4)
p97 (4)
PDE (4)
MTH1 (3)
p38 MAPK (3)
Serine/threonin kinase (3)
Mdm2 (3)
MAO (3)
Lipoxygenase (3)
JAK (3)
Histamine Receptor (3)
FGFR (3)
Antifolate (3)
Carbonic Anhydrase (3)
Caspase (3)
Chk (3)
Deubiquitinase (3)
c-RET (3)
Trk receptor (3)
Thrombin (3)
Tyrosine Kinases (3)
TLR (2)
Syk (2)
Tyrosinase (2)
Retinoid Receptor (2)
Transferase (2)
DNA Alkylator/Crosslinker (2)
EGFR (2)
DNA Methyltransferase (2)
Estrogen/progestogen Receptor (2)
GPR (2)
Antibiotic (2)
Arginase (2)
Adenosine Receptor (2)
Adrenergic Receptor (2)
Akt (2)
ABC (2)
AMPK (2)
HCV Protease (2)
JNK (2)
IRE1 (2)
IκB/IKK (2)
NMDAR (2)
Nrf2 (2)
NADPH (2)
MLK (2)
MMP (2)
SGK (2)
ROS (2)
SARS-CoV (2)
RAAS (2)
Raf (1)
Ras (1)
Rho (1)
ribosome (1)
PI4K (1)
Proteasome (1)
Serine Protease (1)
S6 Kinase (1)
Sodium Channel (1)
Phospholipase (1)
P2 Receptor (1)
MNK (1)
MPO (1)
MRP (1)
Liver X Receptor (1)
LRRK2 (1)
MAPK (1)
Influenza Virus (1)
KSP (1)
Hydrogenase (1)
IDO (1)
IGF-1R (1)
Androgen Receptor (1)
5-HT Receptor (1)
ALK (1)
Aminopeptidase (1)
Aromatase (1)
Apoptosis inducer (1)
Antioxidant (1)
cholecystokinin (1)
c-Kit (1)
c-Met/HGFR (1)
c-Fms (1)
Carboxypeptidase(CPG2) (1)
BTK (1)
GRK (1)
HBV (1)
Hck (1)
Hedgehog/Smoothened (1)
HER (1)
HIF (1)
Gap Junction Protein (1)
Glucocorticoid Receptor (1)
Glucokinase (1)
GluR (1)
DNA Stain (1)
Dopamine Receptor (1)
Electron transport (1)
E1/E2/E3 Enzyme (1)
Cysteine Protease (1)
Wee1 (1)
TAM Receptor (1)
STAT (1)
TGF-beta/Smad (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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