抗癌天然产物库

Antitumor Natural Products Library
产品编号 L6700
  库化合物信息   Excel SDF

癌症是严重危害人类健康的疾病, 从天然产物中寻找预防和治疗恶性肿瘤的活性成分始终是国内外肿瘤药物开发的热门领域,众多药物化学家们一直在致力于天然抗瘤药物的开发。随着对肿瘤发生、恶变的分子机制研究不断深入,人们以肿瘤发生发展过程中相关酶、受体为作用靶点, 筛选出一系列新的有潜在抗癌活性的天然先导化合物。据权威机构统计,从1981年至今,99种小分子抗癌药物中的79种是以天然产物为基础研制成功的,例如紫杉烷类、喜树碱类和长春碱类等热门抗肿瘤药物。天然产物是一个巨大的药物开发宝库,天然产物的研究与开发历来是人类寻找新药以及向疾病作斗争的重要手段。借助天然产物的结构先导、修饰和改造也促进了合成药物的迅速发展。

TargetMol精心筛选1059种来源于植物、动物或微生物的具有已知或潜在抗肿瘤活性天然产物,性价比高,能够为您提供肿瘤药物开发、天然先导化合物筛选等研究的有力工具。

抗癌天然产物库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 146400.00
250 μL * 10 mM (in DMSO) 245068.00
1 mg 245068.00
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产品描述

  • 1059种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS和HCS。
  • 全部产品活性已知:提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础;
  • 来源清晰:精选来自动物、植物、微生物的已知活性天然产物;更具体到植物种属,并标注准确英文名与拉丁名,方便您的后期研究确证。
  • 信息全面:从化合物结构到溶解度,从信号通路、作用靶点到生物活性信息均有详细描述。
  • 性价比高:剔除了价格昂贵但成药性差的天然产物,让您用更少的成本得到更多高品质的天然产物。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L6700)

化合物库组成

NF-κB (63)
Apoptosis (44)
Autophagy (34)
Antioxidant (32)
TNF (32)
AChR (31)
Endogenous Metabolite (29)
P450 (26)
Estrogen/progestogen Receptor (25)
ERK (24)
COX (24)
Antibacterial (24)
STAT (23)
DNA/RNA Synthesis (22)
Apoptosis inducer (21)
PKC (20)
Topoisomerase (19)
Akt (19)
Dehydrogenase (18)
Caspase (18)
Microtubule Associated (16)
IL Receptor (16)
p38 MAPK (16)
PPAR (16)
Tyrosinase (15)
Vitamin (15)
BCL (15)
AMPK (14)
EGFR (14)
GABA Receptor (13)
Potassium Channel (13)
Adrenergic Receptor (12)
5-HT Receptor (12)
Amino Acids and Derivatives (11)
Antiviral (11)
PI3K (11)
PDE (10)
ROS (10)
Sodium Channel (10)
MAO (10)
Bcr-Abl (9)
Wnt/beta-catenin (9)
TRP/TRPV Channel (8)
VEGFR (8)
TGF-beta/Smad (8)
ATPase (8)
MMP (8)
JNK (8)
NOS (8)
mTOR (7)
Lipoxygenase (7)
MAPK (7)
Calcium Channel (7)
Antibiotic (7)
Antifection (6)
Androgen Receptor (6)
JAK (6)
p53 (6)
HIF (6)
HIV Protease (6)
Sirtuin (6)
ribosome (5)
UGT (5)
PARP (5)
HMG-CoA Reductase (5)
HSP (5)
Histamine Receptor (5)
Glucokinase (5)
HDAC (5)
NOD (5)
IκB/IKK (5)
MEK (5)
CaMK (5)
Beta Amyloid (5)
Antifungal (5)
Dopamine Receptor (5)
Epigenetic Reader Domain (5)
Carbonic Anhydrase (4)
CDK (4)
BACE (4)
Nucleoside Antimetabolite/Analog (4)
Opioid Receptor (4)
PKA (4)
Prostaglandin Receptor (4)
P-gp (4)
Phospholipase (4)
Parasite (3)
RAAS (3)
Retinoid Receptor (3)
Tyrosine Kinases (3)
TLR (3)
Trk receptor (3)
Src (3)
Syk (3)
Nrf2 (3)
NMDAR (3)
NADPH (3)
Hedgehog/Smoothened (3)
HER (3)
GPCR19 (3)
GSK-3 (3)
IDO (3)
IGF-1R (3)
HSV (3)
Aromatase (3)
Adenosine Receptor (3)
CXCR (3)
c-Myc (2)
cell cycle arrest (2)
Casein Kinase (2)
DNA Alkylation (2)
DNA gyrase (2)
DNA Methyltransferase (2)
FAK (2)
Fatty Acid Synthase (2)
FGFR (2)
ATP Citrate Lyase (2)
Arginase (2)
HIF/HIF Prolyl-Hydroxylase (2)
Glucocorticoid Receptor (2)
HCV Protease (2)
Histone Methyltransferase (2)
GR (2)
GluR (2)
FXR (2)
Mitophagy (2)
MRP (2)
PAFR (2)
IAP (2)
Lipid (2)
Telomerase (2)
Transferase (2)
transporter (2)
Reductase (2)
S6 Kinase (2)
Serine/threonin kinase (2)
PDGFR (2)
Pim (2)
PKM (2)
Platelet aggregation (2)
PLK (1)
PDK (1)
PGE Synthase (1)
OX Receptor (1)
P2X Receptor (1)
SGLT (1)
Reverse Transcriptase (1)
Raf (1)
Proteasome (1)
PTEN (1)
Thrombin (1)
Thyroid hormone receptor(THR) (1)
Survivin (1)
ROR (1)
Somatostatin (1)
Xanthine Oxidase (1)
LTR (1)
lysosomal autophagy (1)
LDL (1)
Lipase (1)
Melatonin Receptor (1)
Mdm2 (1)
MPO (1)
Mitochondrial Metabolism (1)
PAI-1 (1)
PAK (1)
NOD-like Receptor (NLR) (1)
Norepinephrine (1)
Gamma-secretase (1)
Glucagon Receptor (1)
Glutathione reductase (1)
GlyT (1)
GST (1)
hCE (1)
Hexokinase (1)
Influenza Virus (1)
Integrin (1)
IRAK (1)
Hydroxylase (1)
ATM/ATR (1)
Cannabinoid Receptor (1)
BVDV (1)
Adiponectin receptor (1)
ABC (1)
AChE (1)
AhR (1)
ALK (1)
Aminopeptidase (1)
Antifolate (1)
Free radical scavengers (1)
Ferroptosis (1)
Fas/FasL (1)
FAAH (1)
Factor Xa (1)
DYRK (1)
Estrogen Receptor/ERR (1)
CCR (1)
CFTR (1)
Chloride channel (1)
c-Met/HGFR (1)
DHFR (1)
DNA (1)
Cysteine Protease (1)
Decarboxylase (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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