抗肥胖化合物库

Anti-obesity Compound Library
产品编号 L7100
  库化合物信息   Excel SDF

近年来肥胖已成为全球普遍的公共健康问题,肥胖是一种由多种因素(遗传、饮食习惯、生活方式和环境)相互作用引起的复杂的疾病,通常伴随着胰岛素抵抗、氧化应激和炎症标志物表达增加,导致体内脂肪含量增加。肥胖容易引起糖尿病,高血压,动脉硬化等多种代谢紊乱性疾病。肥胖管理的基本策略(如饮食控制、体育运动、手术治疗)分别具有不同程度的局限性和副作用。因此,许多研究人员试图从食物或药物中寻找出抗肥胖的生物活性成分,特别是抑制脂肪等高能量物质吸收过程的化合物、促进脂肪分解的化合物、增加机体代谢能量消耗的化合物,这些化合物包括:脂肪酶抑制剂、a-葡萄糖苷酶抑制剂、麦芽糖酶抑制剂等。

随着经济发展,肥胖问题已成为全球面临的严峻问题,所以科学家对肥胖的关注和研究更是有增无减。通过对文献和公开资料的整理,我们精心筛选了1176个抗肥胖化合物组成抗肥胖化合物库,适合于抗肥胖的相关研究。

抗肥胖化合物库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 149764.00
250 μL * 10 mM (in DMSO) 269592.00
1 mg 269592.00
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产品描述

  • 1176个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选;
  • 提供产品的来源、化学信息和生物学信息,为筛选提供理论方向和研究基础;
  • 结构多样,药效显著,可渗透细胞;
  • NMR和HPLC技术保证产品高纯度。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L7100)

化合物库组成

PI3K (99)
PPAR (54)
VEGFR (52)
mTOR (51)
TNF (46)
p38 MAPK (42)
NF-κB (42)
ERK (40)
Raf (38)
Akt (36)
Wnt/beta-catenin (33)
JAK (32)
COX (30)
Adrenergic Receptor (29)
GSK-3 (29)
Glucocorticoid Receptor (28)
DNA-PK (26)
MEK (25)
PDGFR (25)
P450 (23)
STAT (23)
GR (23)
AMPK (23)
ROS (21)
Src (21)
S6 Kinase (20)
c-Kit (20)
Sirtuin (19)
Phospholipase (19)
EGFR (18)
ATM/ATR (18)
Hedgehog/Smoothened (18)
FLT (18)
IL Receptor (18)
IκB/IKK (17)
FGFR (17)
CDK (17)
Dehydrogenase (16)
GluR (16)
JNK (16)
Lipoxygenase (16)
Potassium Channel (15)
PKC (14)
TGF-beta/Smad (14)
ALK (14)
Tyrosine Kinases (13)
AChR (12)
Antioxidant (11)
Bcr-Abl (11)
SGLT (11)
Vitamin (10)
Lipase (10)
MAPK (10)
Glucokinase (10)
FAAH (9)
HMG-CoA Reductase (9)
Androgen Receptor (9)
c-RET (9)
PKA (9)
c-Met/HGFR (8)
DPP-4 (8)
5-HT Receptor (8)
Autophagy (8)
IGF-1R (8)
GPR (7)
Fatty Acid Synthase (6)
FXR (6)
Liver X Receptor (6)
Cannabinoid Receptor (6)
Carbonic Anhydrase (6)
Endogenous Metabolite (6)
Estrogen/progestogen Receptor (6)
Dopamine Receptor (6)
DNA Alkylation (6)
Caspase (6)
PDE (6)
PDK (6)
MMP (6)
TLR (6)
transporter (5)
PERK (5)
RAAS (5)
CETP (5)
DNA/RNA Synthesis (5)
Casein Kinase (5)
Aurora Kinase (5)
GABA Receptor (5)
NMDAR (4)
NOD (4)
Amino Acids and Derivatives (4)
Antifection (4)
Epigenetic Reader Domain (4)
c-Fms (4)
Chk (4)
Porcupine (4)
NADPH (4)
Trk receptor (4)
TAM Receptor (4)
ROCK (4)
Serine Protease (4)
Ras (4)
Tie-2 (3)
Tyrosinase (3)
cAMP (3)
ABC (3)
ATPase (3)
Beta Amyloid (3)
MLK (3)
HSV (3)
GlyT (3)
HDAC (3)
Histamine Receptor (3)
HIF (2)
HSP (2)
Histone Methyltransferase (2)
Hck (2)
GPCR19 (2)
FAK (2)
Hydroxylase (2)
Integrin (2)
LRRK2 (2)
LTR (2)
MAO (2)
Microtubule Associated (2)
Norepinephrine (2)
NOS (2)
Nrf2 (2)
Calcium Channel (2)
BACE (2)
BCL (2)
ATP Citrate Lyase (2)
Aromatase (2)
Adiponectin receptor (2)
Apoptosis (2)
Ephrin Receptor (2)
E1/E2/E3 Enzyme (2)
CSF-1R (2)
TRP/TRPV Channel (2)
UGT (2)
TOPK (2)
Thrombin (2)
Reductase (2)
Reverse Transcriptase (2)
SGK (2)
Sodium Channel (2)
Syk (2)
SIK (2)
MNK (2)
MPO (2)
MRP (2)
p53 (2)
Prostaglandin Receptor (2)
Proteasome (1)
PTP1B (1)
RAR/RXR (1)
PKM (1)
PI4K (1)
PAI-1 (1)
PARP (1)
Phosphatase (1)
Monocarboxylate transporter (1)
NADPH-oxidase (1)
OX Receptor (1)
Smo (1)
ribosome (1)
RIP kinase (1)
Retinoid Receptor (1)
Thyroid hormone receptor(THR) (1)
Transferase (1)
Vasopressin Receptor (1)
Wnk (1)
CXCR (1)
Cysteine Protease (1)
CPT (1)
Chloride channel (1)
cholecystokinin (1)
CFTR (1)
CAT (1)
cell cycle arrest (1)
DHFR (1)
Discoidin Domain Receptor (DDR) (1)
DNA (1)
Arginase (1)
Antiviral (1)
Antifungal (1)
Antibacterial (1)
ACK (1)
Adenosine Receptor (1)
ASK (1)
CaMK (1)
BMI-1 (1)
BTK (1)
OAT (1)
Opioid Receptor (1)
Mitochondrial Metabolism (1)
Mitophagy (1)
Mdm2 (1)
MELK (1)
lysosomal autophagy (1)
Lipid (1)
LDL (1)
IRAK (1)
Isocitrate Dehydrogenase (IDH) (1)
IAP (1)
Immunology & Inflammation related (1)
Ferroptosis (1)
Gamma-secretase (1)
Glucagon Receptor (1)
Glutaminase (1)
FOXO1 (1)
Free radical scavengers (1)
Hexokinase (1)
GST (1)
HBV (1)
HIV Protease (1)
Histone Acetylation (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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