中药抗炎分子库

Anti-Inflammatory Tradition Chinese Medicine Library
产品编号 L6710
  库化合物信息   Excel SDF

炎症是临床常见的一个病理过程,可以生于机体各部位的组织和各器官,抗炎药物在临床上已经是仅次于抗感染药物的第二大类药物。临床上广泛使用的抗炎药物是非甾体类抗炎药物和肾上腺皮质激素类药物,但是两者均被报道有诸多的不良反应。中药因其资源丰富,副作用少等特点开始进入人们的视线。大量报道证实,很多中药都具有不同程度的对抗各种炎症的作用。随着研究的深入,已报道出单味中药、中药复方制剂、中草药有效部位和有效成分等均有抗炎作用,以中药为基源的抗炎成分、机理研究与创新药物的开发成为世界范围内学者们研究的热点。

TargetMol精选了319种炎症相关的中药单体,来源包含金银花、黄连、黄芩、三七等多种中药,这些中药单体有黄酮、皂苷、萜类、生物碱等结构,多样性好,具有较明确的活性信息,为中药抗炎相关研究提供有力工具。

中药抗炎分子库
规格 价格/RMB
100 μL * 10 mM (in DMSO) 47260.00
250 μL * 10 mM (in DMSO) 78770.00
1 mg 78770.00
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产品描述

  • 319种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具;
  • 结构多样,包含黄酮、皂苷、萜类、生物碱等类别;
  • 靶向COX、CCR、STAT、TGFβ等炎症相关靶点;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

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包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
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化合物库组成

NF-κB (27)
TNF (22)
Antioxidant (19)
COX (16)
STAT (15)
MMP (13)
IL Receptor (13)
EGFR (10)
p38 MAPK (9)
P450 (8)
Antibacterial (8)
ERK (7)
Tyrosinase (7)
TGF-beta/Smad (6)
Lipoxygenase (6)
Akt (6)
AChR (5)
Antiviral (5)
Autophagy (5)
NOS (5)
Prostaglandin Receptor (5)
PPAR (4)
VEGFR (4)
Caspase (4)
Dehydrogenase (3)
Antifection (3)
Adrenergic Receptor (3)
AMPK (3)
JAK (3)
JNK (3)
GABA Receptor (3)
5-HT Receptor (3)
Phospholipase (3)
PKA (3)
PKC (3)
Potassium Channel (2)
Reductase (2)
UGT (2)
Src (2)
TRP/TRPV Channel (2)
IκB/IKK (2)
HIV Protease (2)
HDAC (2)
NOD (2)
Adenosine Receptor (2)
Antifungal (2)
DNA/RNA Synthesis (2)
Endogenous Metabolite (2)
CXCR (2)
BCL (2)
Bcr-Abl (2)
BVDV (1)
Cannabinoid Receptor (1)
CCR (1)
CDK (1)
cell cycle arrest (1)
BACE (1)
Epigenetic Reader Domain (1)
Antibiotic (1)
Apoptosis (1)
Apoptosis inducer (1)
Aromatase (1)
Adiponectin receptor (1)
advanced glycation end products (1)
Androgen Receptor (1)
Aminopeptidase (1)
Opioid Receptor (1)
MAO (1)
MAPK (1)
p53 (1)
PAI-1 (1)
PARP (1)
PDE (1)
PGE Synthase (1)
Phosphatase (1)
HER (1)
HIF (1)
FAAH (1)
Gamma-secretase (1)
Glucokinase (1)
hCE (1)
HSV (1)
IAP (1)
IDO (1)
Immunology & Inflammation related (1)
Influenza Virus (1)
Topoisomerase (1)
Transferase (1)
TLR (1)
Wnt/beta-catenin (1)
Tyrosine Kinases (1)
ROS (1)
S6 Kinase (1)
Serine/threonin kinase (1)
Sirtuin (1)
Survivin (1)
Syk (1)
Telomerase (1)
PI3K (1)
Proteasome (1)
PTEN (1)
PTP1B (1)
RAAS (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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