抗癌化合物库

Anti-Cancer Compound Library
产品编号 L2100
  库化合物信息   Excel SDF

在过去的几十年中癌症的研究和治疗取得了巨大的成功,但癌症仍然是人类面临的巨大挑战,给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征,表现出无限的增殖潜能,维持自身生长信号的持续稳定,逃避应激信号(例如治疗药物)诱导的细胞凋亡,刺激血管生长,为肿瘤提供营养,同时逃避免疫系统防御和诱导局部慢性炎症,发挥其侵袭和转移能力,表现出异常的代谢活动,并通过突变和表观遗传机制显著改变全基因组的稳定性。

我们根据上述癌细胞显著不同的特征和异常的代谢活动,精心筛选了5885个肿瘤相关的小分子化合物,这些化合物都是调节肿瘤细胞代谢、增殖、侵袭、转移通路上的小分子,可用于肿瘤相关的研究以及抗肿瘤药物的筛选,可用于高通量、高内涵筛选。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
抗癌化合物库
规格 价格/RMB
30 μL * 10 mM (in DMSO) 177400.00
100 μL * 10 mM (in DMSO) 394200.00
250 μL * 10 mM (in DMSO) 682660.00
1 mg 682660.00
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产品描述

  • 5885种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
  • 产品经过临床验证和临床实验,具有生物安全保障和一定的生物活性;
  • 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具; 
  • 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS检测技术保证产品高纯度和高质量,减少假阳性发生概率。

化合物库定制

我们的化合物库可以灵活定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L2100)

化合物库组成

AChR (130)
5-HT Receptor (120)
COX (120)
PI3K (115)
DNA/RNA Synthesis (113)
CDK (111)
Adrenergic Receptor (107)
EGFR (106)
VEGFR (103)
Autophagy (84)
Epigenetic Reader Domain (78)
NF-κB (77)
HDAC (74)
Estrogen/progestogen Receptor (73)
Apoptosis (70)
Histamine Receptor (69)
PPAR (68)
Dehydrogenase (67)
JAK (64)
Src (62)
TNF (60)
mTOR (60)
Potassium Channel (60)
Histone Methyltransferase (59)
Bcr-Abl (59)
Antibacterial (58)
Dopamine Receptor (58)
Topoisomerase (58)
PDGFR (57)
Microtubule Associated (56)
FGFR (55)
ERK (53)
FLT (51)
Raf (50)
PKC (48)
STAT (48)
p38 MAPK (47)
P450 (47)
Akt (47)
c-Kit (46)
Wnt/beta-catenin (46)
c-Met/HGFR (45)
PDE (45)
ALK (41)
GABA Receptor (41)
BCL (39)
HSP (38)
AMPK (37)
GSK-3 (35)
IL Receptor (35)
RAAS (34)
Antioxidant (34)
Tyrosine Kinases (34)
Sodium Channel (34)
Glucocorticoid Receptor (33)
PARP (33)
MEK (32)
Antibiotic (32)
Androgen Receptor (31)
Caspase (31)
Endogenous Metabolite (31)
DNA-PK (31)
Aurora Kinase (29)
MAO (28)
Sirtuin (28)
BTK (27)
Carbonic Anhydrase (26)
Antifection (26)
ATPase (26)
GR (26)
Integrin (26)
JNK (25)
HIF (25)
Parasite (25)
TRP/TRPV Channel (25)
TAM Receptor (24)
HER (24)
IκB/IKK (24)
ATM/ATR (24)
Apoptosis inducer (24)
Antiviral (23)
Amino Acids and Derivatives (23)
DNA Alkylation (23)
HIV Protease (23)
S6 Kinase (23)
PKA (23)
Proteasome (23)
TGF-beta/Smad (23)
Tyrosinase (22)
Trk receptor (22)
Histone Demethylase (22)
c-RET (22)
CXCR (22)
Calcium Channel (22)
Gamma-secretase (20)
Hedgehog/Smoothened (20)
ROS (20)
Retinoid Receptor (20)
p53 (19)
GPR (19)
Cysteine Protease (18)
Casein Kinase (18)
Ras (18)
MAPK (18)
Mdm2 (18)
MMP (18)
Vitamin (18)
TLR (17)
Serine Protease (17)
LRRK2 (17)
NOS (17)
ROCK (16)
IGF-1R (16)
FAK (16)
Syk (16)
CCR (15)
CaMK (15)
Adenosine Receptor (15)
Reverse Transcriptase (15)
Norepinephrine (15)
Phospholipase (14)
MRP (14)
Chk (14)
DUB (14)
DNA gyrase (13)
DNA Methyltransferase (13)
GluR (13)
Lipoxygenase (13)
PLK (13)
Transferase (13)
Serine/threonin kinase (13)
NADPH (12)
IDO (12)
Glucokinase (12)
CFTR (11)
Beta Amyloid (11)
Aromatase (11)
HIF/HIF Prolyl-Hydroxylase (11)
HMG-CoA Reductase (11)
Pim (11)
S1P Receptor (11)
Prostaglandin Receptor (10)
NMDAR (10)
Opioid Receptor (10)
PERK (10)
Antifungal (10)
c-Fms (10)
DHFR (10)
CSF-1R (10)
Thrombin (10)
E1/E2/E3 Enzyme (9)
Fatty Acid Synthase (9)
PDK (9)
Nucleoside Antimetabolite/Analog (9)
Phosphatase (9)
Rho (9)
HSV (9)
Histone Acetyltransferase (8)
Liver X Receptor (8)
ribosome (8)
Proton pump (8)
Nrf2 (8)
P-gp (8)
HCV Protease (8)
BACE (8)
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Cannabinoid Receptor (7)
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PAK (7)
PKM (7)
Hydroxylase (7)
Kinesin (7)
Telomerase (7)
transporter (7)
UGT (7)
Tie-2 (6)
IAP (6)
Monocarboxylate transporter (6)
ROR (6)
PD-1/PD-L1 (6)
NOD (6)
Chloride channel (6)
CAT (6)
ABC (6)
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Discoidin Domain Receptor (DDR) (5)
DNA (5)
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Factor Xa (5)
BMI-1 (5)
P2 Receptor (5)
p97 (5)
Platelet aggregation (5)
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MPO (5)
Mitochondrial Metabolism (5)
NAMPT (5)
MLK (5)
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SGLT (5)
STING (5)
Sigma receptor (4)
SGK (4)
MNK (4)
Lipase (4)
LTR (4)
Porcupine (4)
PYK2 (4)
PAI-1 (4)
OCT (4)
cholecystokinin (4)
ATP Citrate Lyase (4)
Arginase (4)
Annexin A (4)
Free radical scavengers (4)
Hck (4)
GRK (4)
Dynamin (4)
DYRK (4)
DPP-4 (4)
DprE1 (3)
Deubiquitinase (3)
CRM1 (3)
GNRH Receptor (3)
GPCR19 (3)
GST (3)
GTPase (3)
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ASK (3)
ACAT (3)
ACK (3)
Aminopeptidase (3)
CETP (3)
cell cycle arrest (3)
cAMP (3)
OX Receptor (3)
OXPHOS (3)
Na-K-Cl cotransporter (3)
PAD (3)
PAFR (3)
PTEN (3)
lysosomal autophagy (3)
Lipid (3)
LPA Receptor (3)
LIM Kinase (3)
LDL (3)
Mitophagy (3)
MTH1 (3)
IRE1 (3)
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Thyroid hormone receptor(THR) (3)
Vasopressin Receptor (3)
VDA (2)
Wee1 (2)
Wnk (2)
TOPK (2)
SIK (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
IRAK (2)
KSP (2)
Hippo pathway (2)
Hexokinase (2)
Phosphorylase (2)
PI4K (2)
RIP kinase (2)
Reactive Oxygen Species (2)
PED (2)
NPC1L1 (2)
Carboxypeptidase(CPG2) (2)
BCRP (2)
CaSR (2)
AChE (2)
Acyltransferase (2)
GPX (2)
Haspin Kinase (2)
Glutaminase (2)
Glutathione reductase (2)
GlyT (2)
Gap Junction Protein (2)
GHSR (2)
Decarboxylase (2)
DNA Alkylator/Crosslinker (2)
FAAH (2)
Fas/FasL (1)
Estrogen Receptor/ERR (1)
Endothelin Receptor (1)
Electron transport (1)
DNA Stain (1)
Dehydrogenase inhibitor (1)
Glucagon Receptor (1)
GluCls (1)
FOXO1 (1)
Glutathione Peroxidase (1)
hCE (1)
Guanylate cyclase (1)
Adiponectin receptor (1)
Acetyl-CoA Carboxylase (1)
advanced glycation end products (1)
Cell wall (1)
CPT (1)
Beta-Secretase (1)
BVDV (1)
NOD-like Receptor (NLR) (1)
NKCC (1)
P2X Receptor (1)
OAT (1)
PGE Synthase (1)
Salt-Inducible Kinase (1)
SARS-CoV (1)
RAR/RXR (1)
Histone Acetylation (1)
Hydrogenase (1)
Keap1-Nrf (1)
Isocitrate Dehydrogenase (IDH) (1)
Integrase (1)
Interleukin Related (1)
Immunology & Inflammation related (1)
MT Receptor (1)
Neurokinin receptor (1)
NADPH-oxidase (1)
Monoamine Transporter (1)
LHRH (1)
MALT (1)
Melatonin Receptor (1)
MELK (1)
MicroRNA (1)
Smo (1)
Serotonin Transporter (1)
Somatostatin (1)
Stearoyl-CoA Desaturase (SCD) (1)
Stemness kinase (1)
Thioredoxin (1)
TACC (1)
Virus Protease (1)
Xanthine Oxidase (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat Fasiglifam TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS-754807 Enmetazobactam
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG-208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol TRIA-662 MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv 3-Pyridinemethanol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 BMP signaling agonist sb4 Daclatasvir Daclatasvir dihydrochloride NADPH tetracyclohexanamine AZD-8055 Vistusertib PAβN dihydrochloride HZ-1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin-3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A 78U Tenovin-6 Normetanephrine hydrochloride Triclocarban CUDC-101 Chlorpropham Pyridostigmine bromide Zacopride hydrochloride PF-04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine dihydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
陶术生物的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务,也不为任何个人提供产品和服务。陶素|陶素生化|陶术|陶术生物
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