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通路靶点分类

细胞的一切生命活动都起于信号。信号通路几乎渗透于所有的细胞生命活动:代谢、分裂、分化、功能、凋亡等。因此,信号通路和通路上相关靶点的相关研究对于探明疾病发病机制、发现靶向药物至关重要。TargetMol的活性化合物库按照通路靶点分为多种化合物库,如MAPK抑制剂库、离子通道库、自噬库、5-羟色胺分子库等,涵盖多条热门信号通路和多种热门靶点,是您研究疾病发病机制、药物作用机制或细胞诱导分化的好助手。

FDA-Approved Kinase Inhibitor Library L1610 FDA 上市激酶抑制剂库 280 compounds Calcium Antagonist Library L7200 钙通道分子库 143 compounds Phosphatase Inhibitor Library L9100 磷酸酶抑制剂化合物库 80 compounds HIF-1 Signaling Pathway Compound Library L8500 HIF-1化合物库 1352 compounds AMPK-Targeted Compound Library L1120 AMPK靶向分子库 64 compounds GPCR Compound Library L1500 GPCR靶点分子库 1633 compounds Autophagy Compound Library L3200 自噬库 1248 compounds Neurotransmitter Receptor Compound Library L2610 神经递质受体化合物库 1290 compounds TGF-beta/Smad Compound Library L4100 TGF-β/Smad靶点化合物库 180 compounds Histamine & Melatonin Receptor-Targeted Library L3300 组胺&褪黑色素化合物库 155 compounds Serotonin Receptor-Targeted Compound Library L2800 5-羟色胺分子库 275 compounds Methylation Compound Library L3510 甲基化化合物库 131 compounds Cytokine Inhibitor Library L3600 细胞因子抑制剂库 613 compounds Sodium Channel Blocker Library L7400 钠通道分子库 128 compounds Mitochondria-Targeted Compound Library L5300 线粒体靶向库 447 compounds Ion Channel Inhibitor Library L2300 离子通道库 946 compounds Exosome Compound Library L9420 外泌体相关化合物库 54 compounds Microtubule-Targeted Compound Library L1110 微管靶向化合物库 80 compounds Inhibitor Library L2000 抑制剂库 5700 compounds NF-κB Signaling Compound Library L3800 NF-κB 通路分子库 560 compounds MAPK Inhibitor Library L1400 MAPK 抑制剂库 367 compounds Kinase Inhibitor Library L1600 激酶抑制剂库 2230 compounds Cell Cycle Compound Library L8100 细胞周期化合物库 695 compounds Wnt/Hedgehog/Notch Compound Library L4300 Wnt/Hedgehog/Notch 通路化合物库 240 compounds DNA Damage & Repair Compound Library L3900 DNA 损伤和修复分子库 937 compounds Ferroptosis Compound Library L8700 铁死亡化合物库 800 compounds Epigenetics Compound Library L1200 表观遗传库 960 compounds Apoptosis Compound Library L9000 细胞凋亡化合物库 1796 compounds Ubiquitination Compound Library L8600 泛素化化合物库 214 compounds GPCR Compound Library Plus L1580 GPCR库Plus 338 compounds Cytoskeletal Signaling Pathway Compound Library L1310 细胞骨架化合物库 590 compounds Protease Inhibitor Library L1100 蛋白酶抑制剂库 344 compounds Potassium Channel Blocker Library L7300 钾通道分子库 160 compounds JAK-STAT Compound Library L3700 JAK-STAT 化合物库 256 compounds Angiogenesis related Compound Library L4800 血管生成库 1370 compounds Chemokine Inhibitor Library L7600 趋化因子抑制剂库 59 compounds Neuronal Signaling Compound Library L2600 神经信号分子库 2011 compounds Adrenergic Receptor-Targeted Compound Library L2700 肾上腺素能受体化合物库 219 compounds PI3K-AKT-mTOR Compound Library L1300 PI3K/Akt/mTOR 化合物库 425 compounds Tyrosine Kinase Inhibitor Library L2200 酪氨酸激酶分子库 746 compounds Nuclear Receptor Inhibitors Library L1510 核受体化合物库 420 compounds Endoplasmic Reticulum Stress Compound Library L9700 内质网应激化合物库 193 compounds Human Kinases Annotated Library DO5200 人激酶靶向活性化合物库 2500 compounds Human Phosphatases Annotated Library DO5400 人磷酸酶靶向活性化合物库 225 compounds Human GPCR Annotated Library DO5000 人GPCR靶向活性化合物库 5800 compounds Human Transcription Factors Annotated Library DO5600 人转录因子靶向活性化合物库 5278 compounds Human Ion Channels Annotated Library DO5100 人离子通道靶向活性化合物库 394 compounds
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