store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sulforaphene 是从萝卜种子中分离出来的天然产物,对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 283 | 现货 | ||
2 mg | ¥ 395 | 现货 | ||
5 mg | ¥ 663 | 现货 | ||
10 mg | ¥ 997 | 现货 | ||
25 mg | ¥ 1,830 | 现货 | ||
50 mg | ¥ 2,720 | 现货 | ||
100 mg | ¥ 3,970 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 543 | 现货 |
产品描述 | Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals. |
体外活性 | A herbicidal compound was isolated from extracts ofMatthiola incana and identified as Sulforaphene (4-methylsulfinyl-3-butenyl isothiocyanate). CONCLUSIONS: The ED50 of this compound against velvetleaf seedlings was approximately 2×10(-4) M. Glucoraphenin, the glucosinolate that is the natural precursor of Sulforaphene, was less phytotoxic, with an ED50 of near 6×10(-3)M. |
别名 | 油菜 |
分子量 | 175.27 |
分子式 | C6H9NOS2 |
CAS No. | 592-95-0 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (570.55 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 5.7055 mL | 28.5274 mL | 57.0548 mL | 142.6371 mL |
5 mM | 1.1411 mL | 5.7055 mL | 11.411 mL | 28.5274 mL | |
10 mM | 0.5705 mL | 2.8527 mL | 5.7055 mL | 14.2637 mL | |
20 mM | 0.2853 mL | 1.4264 mL | 2.8527 mL | 7.1319 mL | |
50 mM | 0.1141 mL | 0.5705 mL | 1.1411 mL | 2.8527 mL | |
100 mM | 0.0571 mL | 0.2853 mL | 0.5705 mL | 1.4264 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Sulforaphene 592-95-0 Angiogenesis Apoptosis JAK/STAT signaling MAPK NF-Κb Tyrosine Kinase/Adaptors NF-κB ERK EGFR Nuclear factor-κB Epidermal growth factor receptor HER1 inhibit Extracellular signal regulated kinases ErbB-1 Nuclear factor-kappaB Inhibitor 油菜 inhibitor