Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) 是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物,是熊去氧胆酸的代谢物。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 mg | ¥ 260 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 210 | 现货 |
产品描述 | Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, and almost all bile acids in the bile duct, therefore, exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals. |
别名 | Ursodeoxycholylglycine, 甘氨熊胆酸, GUDCA |
分子量 | 449.62 |
分子式 | C26H43NO5 |
CAS No. | 64480-66-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2 mg/mL
DMSO: 60 mg/mL (133.45 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2241 mL | 11.1205 mL | 22.241 mL | 55.6025 mL |
5 mM | 0.4448 mL | 2.2241 mL | 4.4482 mL | 11.1205 mL | |
10 mM | 0.2224 mL | 1.1121 mL | 2.2241 mL | 5.5603 mL | |
20 mM | 0.1112 mL | 0.556 mL | 1.1121 mL | 2.7801 mL | |
50 mM | 0.0445 mL | 0.2224 mL | 0.4448 mL | 1.1121 mL | |
100 mM | 0.0222 mL | 0.1112 mL | 0.2224 mL | 0.556 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Glycoursodeoxycholic acid 64480-66-6 Metabolism Others Endogenous Metabolite inhibit Ursodeoxycholylglycine Inhibitor 甘氨熊胆酸 GUDCA inhibitor