store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 789 | 现货 | ||
5 mg | ¥ 1,992 | 现货 | ||
10 mg | ¥ 3,154 | 现货 | ||
25 mg | ¥ 5,677 | 现货 | ||
50 mg | ¥ 8,515 | 现货 | ||
100 mg | ¥ 12,772 | 现货 |
产品描述 | FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation. |
体外活性 | FINO2 (10 µM; 24 h) induce ferroptosis and shows iron dependence of lipid peroxidation in HT-1080 cells[1]. |
分子量 | 256.38 |
分子式 | C15H28O3 |
CAS No. | 869298-31-7 |
store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90mg/mL (351mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.9005 mL | 19.5023 mL | 39.0046 mL | 97.5115 mL |
5 mM | 0.7801 mL | 3.9005 mL | 7.8009 mL | 19.5023 mL | |
10 mM | 0.39 mL | 1.9502 mL | 3.9005 mL | 9.7512 mL | |
20 mM | 0.195 mL | 0.9751 mL | 1.9502 mL | 4.8756 mL | |
50 mM | 0.078 mL | 0.39 mL | 0.7801 mL | 1.9502 mL | |
100 mM | 0.039 mL | 0.195 mL | 0.39 mL | 0.9751 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
FINO2 869298-31-7 Apoptosis Ferroptosis FINO 2 FINO-2 Inhibitor inhibitor inhibit