keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WST-8 是水溶性的四唑染料,WTS-8测定法的灵敏度比常规MTS 检测高。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 398 | 现货 | ||
50 mg | ¥ 665 | 现货 | ||
100 mg | ¥ 996 | 现货 | ||
200 mg | ¥ 1,675 | 现货 |
产品描述 | WST-8 is a water-soluble tetrazolium dye, the sensitivity of the WST-8(WST8)-based assay is higher than the conventional MTS-based assay. |
体内活性 | NS1209 could be safely administered to rats undergoing electrically induced SE at doses up to 50 mg/kg followed by intravenous infusion of 5 mg/kg for up to 24h. NS1209 administered as a bolus dose of 10-50 mg/kg (i.p. or i.v.) followed by infusion of 4 or 5 mg/kg h (i.v.) for 2-24h effectively discontinued electrically induced SE in all animals within 30-60 min, and there was no recurrence of SE after a 24-h infusion. Kainate-induced SE was similarly blocked by 10 or 30 mg/kg NS1209 (i.v.). To compare the efficacy and neuroprotective effects of NS1209 with those of diazepam (DZP), one group of rats received DZP (20 mg/kg, i.p. and another dose of 10 mg/kg 6h later). By using the administration protocols described, the anticonvulsant effect of NS1209 was faster and more complete than that of DZP. NS1209 treatment (20 mg/kg bolus followed by 5 mg/kg h infusion for 24 h) was neuroprotective against SE-induced hippocampal neurodegeneration, but to a lesser extent than DZP. |
别名 | WST8 |
分子量 | 601.48 |
分子式 | C20H14N6NaO11S2+ |
CAS No. | 193149-74-5 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50 mg/mL (83.13 mM), Sonication is recommended.
DMSO: 10 mg/mL (16.63 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O / DMSO | 1 mM | 1.6626 mL | 8.3128 mL | 16.6257 mL | 41.5641 mL |
5 mM | 0.3325 mL | 1.6626 mL | 3.3251 mL | 8.3128 mL | |
10 mM | 0.1663 mL | 0.8313 mL | 1.6626 mL | 4.1564 mL | |
H2O | 20 mM | 0.0831 mL | 0.4156 mL | 0.8313 mL | 2.0782 mL |
50 mM | 0.0333 mL | 0.1663 mL | 0.3325 mL | 0.8313 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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