Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 15,000 | 8-10周 | ||
50 mg | ¥ 19,800 | 8-10周 | ||
100 mg | ¥ 25,500 | 8-10周 |
产品描述 | Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors. |
体内活性 | When given simultaneously i.v Vatinoxan alone increases cardiac index and tissue oxygen delivery and has no deleterious adverse effects.In a dose-dependent manner Vatinoxan attenuates or prevents dexmedetomidine's systemic hemodynamic effects. A 50:1 dose ratio (Vatinoxan:dexmedetomidine) induces the least alterations in cardiovascular function[1]. Vatinoxan dose-dependently reduces bradycardia associated with dexmedetomidine and shortens the sedative effect without changing its quality. Vatinoxan may help reduce heart rate reduction in cats consciously administering dexmedetomidine[2]. |
别名 | MK-467 hydrochloride, L-659066 hydrochloride |
分子量 | 454.97 |
分子式 | C20H27ClN4O4S |
CAS No. | 130466-38-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 133 mg/mL (292.33 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 2.1979 mL | 10.9897 mL | 21.9795 mL | 54.9487 mL |
5 mM | 0.4396 mL | 2.1979 mL | 4.3959 mL | 10.9897 mL | |
10 mM | 0.2198 mL | 1.099 mL | 2.1979 mL | 5.4949 mL | |
20 mM | 0.1099 mL | 0.5495 mL | 1.099 mL | 2.7474 mL | |
50 mM | 0.044 mL | 0.2198 mL | 0.4396 mL | 1.099 mL | |
100 mM | 0.022 mL | 0.1099 mL | 0.2198 mL | 0.5495 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Vatinoxan hydrochloride 130466-38-5 GPCR/G Protein Neuroscience Adrenergic Receptor L 659066 Hydrochloride MK-467 hydrochloride MK 467 Hydrochloride L-659066 hydrochloride Vatinoxan Hydrochloride MK467 Hydrochloride MK-467 Hydrochloride L-659066 Hydrochloride L659066 Hydrochloride Inhibitor inhibitor inhibit