Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vasicinone 是一种喹唑啉类生物碱,分离自凡士林植物中。它是具有研究帕金森病和其他氧化应激相关神经退行性疾病的潜力。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 959 | 现货 | ||
5 mg | ¥ 2,380 | 现货 | ||
10 mg | ¥ 3,530 | 现货 | ||
25 mg | ¥ 5,730 | 现货 | ||
50 mg | ¥ 7,830 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,480 | 现货 |
产品描述 | Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803. |
体外活性 | The aerial parts of Peganum harmala L. (APP) is a well-known and effective herbal medicine in China, and has been commonly used for treating various ailments, including cough and asthma. OBJECTIVES: To evaluate the antitussive, expectorant, and bronchodilating effects of the quinazoline alkaloids (±)-vasicine (VAS), deoxyvasicine (DVAS) (both isolated from the alkaloid fraction of APP) and (±)-Vasicinone (VAO) (synthesized from VAS). CONCLUSIONS:Quinazoline alkaloids VAS, VAO, and DVAS have significant antitussive, expectorant, and bronchodilating activities. VAS, VAO, and DVAS are the active ingredients in APP, which can be used to treat respiratory disease. |
分子量 | 202.21 |
分子式 | C11H10N2O2 |
CAS No. | 486-64-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (59.34 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.9454 mL | 24.7268 mL | 49.4535 mL | 123.6338 mL |
5 mM | 0.9891 mL | 4.9454 mL | 9.8907 mL | 24.7268 mL | |
10 mM | 0.4945 mL | 2.4727 mL | 4.9454 mL | 12.3634 mL | |
20 mM | 0.2473 mL | 1.2363 mL | 2.4727 mL | 6.1817 mL | |
50 mM | 0.0989 mL | 0.4945 mL | 0.9891 mL | 2.4727 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Vasicinone 486-64-6 Others Adhatoda quinazoline Parkinson stress Inhibitor inhibit alkaloid vasica oxidative plant neurodegenerative disorders inhibitor