首页 GPCR/G Protein Histamine Receptor SUN 1334H
SUN 1334H
编号 T13040    
CAS 607736-84-5     分子式 C23H28Cl2F2N2O3     分子量 489.38
靶点: H1 receptor(ki);
SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).
选择批次  
纯度 98.00%
规格 库存 单价 数量
1 mg 待询 885.00
5 mg 待询 待询
10 mg 待询 待询
大包装特惠,请咨询
大包装特惠,请咨询

生物活性

产品描述

SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 nM).

靶点活性

H1 receptor(ki),ki: 9.7 nM

体外活性

In CHO-K1/hERG cells,SUN-1334H causes potent inhibition of histamine induced contractions of isolated guinea-pig ileum(IC50 : 0.198 μM)[2].

体内活性

In beagle dogs and ovalbumin-induced rhinitis in guinea pigs, SUN-1334H potently inhibits histamine-induced bronchospasm over 24 hours following oral administration and completely suppresses histamine-induced skin wheal [1]. SUN-1334H shows potent reduction of passive and active cutaneous anaphylactic reactions in skin allergy models. In central nervous system side effects models, SUN-1334H, desloratadine and fexofenadine are devoid of any significant effects[2].

化学信息

分子量

489.38

分子式

C23H28Cl2F2N2O3

CAS

607736-84-5

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.043 ml 10.217 ml 20.434 ml
5 mM 0.409 ml 2.043 ml 4.087 ml
10 mM 0.204 ml 1.022 ml 2.043 ml
50 mM 0.041 ml 0.204 ml 0.409 ml
技术支持
在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-998-7375,或者邮箱 info@tsbiochem.com,直接联系到我们。我们会在24小时内尽快联系您。
订购方式
联系陶素
电话:400-821-2233
传真:021-34692979
邮箱:info@tsbiochem.com


  • 关注公众号
    - 超值特惠
    - 客户福利
    - 业界动态
    - 实用攻略
陶素的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)。