Powder: -20°C for 3 years | In solvent: -80°C for 1 year
S 3304 是一种新型的基质金属蛋白酶抑制剂,能够特异的抑制MMP-2和MMP-9的活性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 913 | 现货 | ||
5 mg | ¥ 2,730 | 现货 | ||
10 mg | ¥ 3,970 | 现货 | ||
25 mg | ¥ 6,480 | 现货 | ||
50 mg | ¥ 8,870 | 现货 | ||
100 mg | ¥ 11,900 | 现货 | ||
500 mg | ¥ 23,900 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,780 | 现货 |
产品描述 | S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9. |
体外活性 | S 3304 is a novel D-tryptophan derivative and a potent, noncytotoxic Matrix metalloproteinases inhibitor. S 3304 most effectively inhibits the activities of MMP-2 and MMP-9 but does not inhibit MMP-1, MMP-3, or MMP-7 and may, therefore, lack the musculoskeletal side effects seen with nonspecific inhibitors [1]. |
体内活性 | S 3304 (p.o., the dose range of 20 to 200 mg/kg) treatment, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 cause effective inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen [1]. |
分子量 | 464.56 |
分子式 | C24H20N2O4S2 |
CAS No. | 203640-27-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83.3 mg/mL (179.31 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.1526 mL | 10.7629 mL | 21.5257 mL | 53.8144 mL |
5 mM | 0.4305 mL | 2.1526 mL | 4.3051 mL | 10.7629 mL | |
10 mM | 0.2153 mL | 1.0763 mL | 2.1526 mL | 5.3814 mL | |
20 mM | 0.1076 mL | 0.5381 mL | 1.0763 mL | 2.6907 mL | |
50 mM | 0.0431 mL | 0.2153 mL | 0.4305 mL | 1.0763 mL | |
100 mM | 0.0215 mL | 0.1076 mL | 0.2153 mL | 0.5381 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
S 3304 203640-27-1 Proteases/Proteasome MMP Inhibitor inhibit S-3304 Matrix metalloproteinases S3304 inhibitor