Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ritodrine hydrochloride (NSC 291565) 是一种 β-2肾上腺素受体激动剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 495 | 现货 | ||
200 mg | ¥ 797 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 381 | 现货 |
产品描述 | Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions. |
别名 | DU21220, 盐酸利托君, Ritodrine HCl, NSC 291565 |
分子量 | 323.82 |
分子式 | C17H21NO3·HCl |
CAS No. | 23239-51-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 200.7 mM
DMSO: 200.7 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O / DMSO | 1 mM | 3.0881 mL | 15.4407 mL | 30.8814 mL | 77.2034 mL |
5 mM | 0.6176 mL | 3.0881 mL | 6.1763 mL | 15.4407 mL | |
10 mM | 0.3088 mL | 1.5441 mL | 3.0881 mL | 7.7203 mL | |
20 mM | 0.1544 mL | 0.772 mL | 1.5441 mL | 3.8602 mL | |
50 mM | 0.0618 mL | 0.3088 mL | 0.6176 mL | 1.5441 mL | |
100 mM | 0.0309 mL | 0.1544 mL | 0.3088 mL | 0.772 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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