生物活性
|
产品描述 |
Ritanserin is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM). |
|
靶点活性 |
5-HT2 receptor,0.9 nM H1 receptor,35 nM D2 receptor,70 nM α1 receptor,97 nM α2 receptor,150 nM |
|
体外活性 |
Ritanserin less active on Histamine-H1 (IC50, 35 nM), Dopamine-D2 (IC50, 70 nM), Adrenergic-α1 (IC50, 97 nM), Adrenergic-α2 receptor (IC50, 150 nM) [1]. |
|
体内活性 |
化学信息
|
分子量 |
477.57 |
|
分子式 |
C27H25F2N3OS |
|
CAS |
87051-43-2 |
|
溶解度 |
DMSO: 25 mg/mL (52.35 mM), Need ultrasonic （ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.094 ml | 10.47 ml | 20.939 ml |
| 5 mM | 0.419 ml | 2.094 ml | 4.188 ml |
| 10 mM | 0.209 ml | 1.047 ml | 2.094 ml |
| 50 mM | 0.042 ml | 0.209 ml | 0.419 ml |
产品操作手册
