Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ridinilazole (SMT19969) 是一种新型的窄谱非吸收性抗生素。它显示出对艰难梭菌的有效抑制作用 (MIC90=0.125 mg/L),并且比甲硝唑 (MIC90 = 8 mg/L) 或万古霉素 (MIC90 = 2 mg/L) 更有效。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 828 | 现货 | ||
2 mg | ¥ 1,090 | 现货 | ||
5 mg | ¥ 1,660 | 现货 | ||
10 mg | ¥ 2,820 | 现货 | ||
25 mg | ¥ 4,760 | 现货 | ||
50 mg | ¥ 6,790 | 现货 | ||
100 mg | ¥ 9,180 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,420 | 现货 |
产品描述 | Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L) or vancomycin (MIC90 = 2 mg/L). |
靶点活性 | C. difficile:8 µg/mL (MIC90) |
体内活性 | ridinilazole , a novel antibacterial currently under development for the treatment of CDI.?Owing to its highly targeted spectrum of activity and ability to spare the normal gut microbiota, ridinilazole provides significant advantages over metronidazole and vancomycin, the mainstay antibiotics for CDI.?Ridinilazole is bactericidal against C. difficile and exhibits a prolonged post-antibiotic effect.?Furthermore, treatment with ridinilazole results in decreased toxin production. |
别名 | SMT19969 |
分子量 | 388.42 |
分子式 | C24H16N6 |
CAS No. | 308362-25-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (141.6 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.5745 mL | 12.8727 mL | 25.7453 mL | 64.3633 mL |
5 mM | 0.5149 mL | 2.5745 mL | 5.1491 mL | 12.8727 mL | |
10 mM | 0.2575 mL | 1.2873 mL | 2.5745 mL | 6.4363 mL | |
20 mM | 0.1287 mL | 0.6436 mL | 1.2873 mL | 3.2182 mL | |
50 mM | 0.0515 mL | 0.2575 mL | 0.5149 mL | 1.2873 mL | |
100 mM | 0.0257 mL | 0.1287 mL | 0.2575 mL | 0.6436 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Ridinilazole 308362-25-6 Microbiology/Virology Antibacterial inhibit Bacterial SMT-19969 SMT 19969 SMT19969 Inhibitor inhibitor