store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Retinyl acetate (Vitamin A acetate) 是一种视黄醇的合成乙酸酯形式衍生物,有抗肿瘤和化学预防活性的潜能。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 396 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 338 | 现货 |
产品描述 | Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important. |
体外活性 | Vitamin A deficiency impairs innate immunity by impeding normal regeneration of mucosal barriers damaged by infection, and by diminishing the function of neutrophils, macrophages, and natural killer cells. Vitamin A is also required for adaptive immunity and plays a role in the development of T both-helper (Th) cells and B-cells. Vitamin A deficiency diminishes antibody-mediated responses directed by Th2 cells, although some aspects of Th1-mediated immunity are also diminished. [1] |
体内活性 | Vitamin A acetate (VAA) (fed on an otherwise conventional diet) responds to 105 semiallogeneic cells (a suboptimal dose) in a host-versus-graft (HvG) reaction in mice, whereas mice on a conventional diet do not. [2] Vitamin A acetate can bring a solid and long-lasting state of tolerance induced by the intravenous injection into newborn CBA mice of lymphoid cells from (CBA X C57BL/10ScSn) F1 hybrids to an end, the effect of which is to increase the proportion of the moiety of the T-cell population that produces IL-2. [3] Vitamin A acetate-supplemented diet develops a positive skin reaction to purified protein derivative of mycobacteria in High-dose Mycobacterium bovis-infected mice, and their spleen cells show an increased IL-2 production in vitro. [4] |
别名 | Vitamin A acetate, Retinyl (Retinol) Acetate, 视黄醇乙酸酯(维生素A醋酸酯), Retinol acetate, 视黄醇乙酸酯 |
分子量 | 328.49 |
分子式 | C22H32O2 |
CAS No. | 127-47-9 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 60 mg/mL (182.6 mM)
DMSO: 60 mg/mL (182.6 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
Ethanol / DMSO | 1 mM | 3.0442 mL | 15.2212 mL | 30.4423 mL | 76.1058 mL |
5 mM | 0.6088 mL | 3.0442 mL | 6.0885 mL | 15.2212 mL | |
10 mM | 0.3044 mL | 1.5221 mL | 3.0442 mL | 7.6106 mL | |
20 mM | 0.1522 mL | 0.7611 mL | 1.5221 mL | 3.8053 mL | |
50 mM | 0.0609 mL | 0.3044 mL | 0.6088 mL | 1.5221 mL | |
100 mM | 0.0304 mL | 0.1522 mL | 0.3044 mL | 0.7611 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Retinyl acetate 127-47-9 Retinyl Vitamin A acetate Retinyl (Retinol) Acetate 视黄醇乙酸酯(维生素A醋酸酯) Inhibitor Vitamin A inhibit Retinol acetate Vitamin A Acetate 视黄醇乙酸酯 Retinol Retinyl Acetate Retinol Acetate inhibitor