Resazurin sodium salt

产品编号 T7650   CAS 62758-13-8
别名: Diazoresorcinol (sodium)

Resazurin sodium salt is a blue non-fluorescent dye,is widely used as a metabolic indicator for living cells

Resazurin sodium salt结构式
Resazurin sodium salt , CAS 62758-13-8
规格 库存 价格/RMB 数量
500 mg 待询 393.00
1 g 待询 480.00
1 mL * 10 mM (in DMSO) 上海现货 148.00
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纯度 96.16%
生物活性
化学信息
存储 & 溶解度
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产品描述 Resazurin sodium salt is a blue non-fluorescent dye,is widely used as a metabolic indicator for living cells
靶点活性 Bacterial
体外活性 Resazurin inhibits the growth of a broad range of N. gonorrhoeae isolates, including those resistant to multiple antibiotics[1]
体内活性 In vivo resazurin did not limit the colonisation of mice with N. gonorrhoeae following vaginal infection. The ineffectiveness of resazurin in vivo is likely due to its interaction with serum albumin, which completely diminishes its antimicrobial activity[1].
细胞实验 Overnight broth cultures were used to inoculate FB containing resazurin sodium salt, resorufin sodium salt , resorufin acetate [Marker Gene Technologies, Eugene, OR; dissolved in dimethyl sulfoxide (DMSO)], resorufin butyrate or resorufin pentyl ether . In select experiments, FB was also supplemented with 3 g/dL bovine serum albumin (BSA) . Immediately following inoculation and 24 h later, cultures were serially diluted and were plated onto chocolate II agar. Plates were incubated at 37 °C in 5% CO2 and individual colonies were enumerated. The limit of detection was 100 CFU/mL[1].
别名 Diazoresorcinol (sodium)
纯度 96.16%
分子量 251.17
分子式 C12H6NNaO4
CAS No. 62758-13-8

存储

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

溶解度

DMSO: 150 mg/mL (597.21 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

溶液 1

文献引用

参考文献
1. Schmitt D M , Connolly K L , Jerse A E , et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo[J]. International Journal of Antimicrobial Agents, 2016:S0924857916301650. 2. Schmitt D M , O'Dee D M , Cowan B N , et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis[J]. Frontiers in Cellular and Infection Microbiology, 2013, 3.

相关化合物库

该产品包含在如下化合物库中:
Bioactive Compound Library Antibiotics Library Antibacterial Activity Library Drug-induced Liver Injury (DILI) Compound Library FDA Approved & Pharmacopeial Drug Library

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

 

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