store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quinpirole Hydrochloride (LY 171555) 作为多巴胺受体D2/D3高亲和力的激动剂,被广泛用于研究人以及小鼠多巴胺受体D2/D3的功能
产品描述 | Quinpirole Hydrochloride (LY 171555), as an agonist with high affinity for dopamine receptor D2/D3, has been widely used to study the function of dopamine receptor D2/D3 in humans and mice |
体内活性 | Examined the functions of the DA D1 receptor (D1R) and DA D2 receptor (D2R) by intrastriatal injection of the D1R agonist SKF38393 and the D2R agonist quinpirole. At threshold doses, quinpirole (1.0 μg/site) produce a dose-dependent increase in locomotor activity compared to vehicle injection,in 6-hydroxydopamine (6-OHDA)-lesioned and control rat[1]. |
别名 | LY 171555, (-)-LY 171555 |
分子量 | 255.79 |
分子式 | C13H22ClN3 |
CAS No. | 85798-08-9 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 45.0 mg/mL (175.9 mM), sonification is recommended.
DMSO: 25.0 mg/mL (97.7 mM), sonification is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O / DMSO | 1 mM | 3.9095 mL | 19.5473 mL | 39.0946 mL | 97.7364 mL |
5 mM | 0.7819 mL | 3.9095 mL | 7.8189 mL | 19.5473 mL | |
10 mM | 0.3909 mL | 1.9547 mL | 3.9095 mL | 9.7736 mL | |
20 mM | 0.1955 mL | 0.9774 mL | 1.9547 mL | 4.8868 mL | |
50 mM | 0.0782 mL | 0.3909 mL | 0.7819 mL | 1.9547 mL | |
H2O | 100 mM | 0.0391 mL | 0.1955 mL | 0.3909 mL | 0.9774 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Quinpirole Hydrochloride 85798-08-9 GPCR/G Protein Neuroscience Dopamine Receptor LY171555 LY 171555 LY-171555 (-)-LY 171555 Inhibitor inhibitor inhibit