Powder: -20°C for 3 years | In solvent: -80°C for 1 year
QNZ46 是一种 NR2C/NR2D 选择性 NMDA 受体非竞争性拮抗剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 253 | 现货 | ||
5 mg | ¥ 497 | 现货 | ||
10 mg | ¥ 872 | 现货 | ||
25 mg | ¥ 1,730 | 现货 | ||
50 mg | ¥ 3,220 | 现货 | ||
100 mg | ¥ 4,690 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 547 | 现货 |
产品描述 | QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist. |
激酶实验 | Biochemical filter-binding assays for detection of FGFR phosphorylation activities : Reaction mixtures contains 8 mM Tris-HCl (pH 7.5), 10 mmol/L HEPES, 5 mM dithiothreitol, 10 μM ATP, 0.5 μCi 33P-ATP, 10 mM MnCl2, 150 mM NaCl, 0.01% Triton X-100, 4% dimethyl sulfoxide, 0.05 mg/mL poly(Glu:Tyr) (4:1, average molecular weight of 20–50 kDa), and 7.5, 7.5, and 16 ng of FGFR1, FGFR3, and FGFR4, respectively, and are incubated at room temperature for 30 minutes followed by termination with 10% H3PO4. The reaction mixtures are transferred to 96-well MAFB filter plates that are washed 3 times with 0.5% H3PO4. After air-drying, the plates are read with a Trilux reader. |
分子量 | 443.41 |
分子式 | C24H17N3O6 |
CAS No. | 1237744-13-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.43 mg/mL (10 mM), Sonification is recommended
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2552 mL | 11.2762 mL | 22.5525 mL | 56.3812 mL |
5 mM | 0.451 mL | 2.2552 mL | 4.5105 mL | 11.2762 mL | |
10 mM | 0.2255 mL | 1.1276 mL | 2.2552 mL | 5.6381 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
QNZ46 1237744-13-6 Membrane transporter/Ion channel Neuroscience NMDAR iGluR QNZ-46 Ionotropic glutamate receptors inhibit Inhibitor QNZ 46 inhibitor