Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂,用于研究多汗症,遗尿,胃肠和膀胱痉挛。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 231 | 现货 | ||
100 mg | ¥ 413 | 现货 | ||
200 mg | ¥ 588 | 现货 | ||
500 mg | ¥ 980 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 152 | 现货 |
产品描述 | Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
别名 | Neopepulsan, 溴丙胺太林, Pro-Banthine, Neometantyl |
分子量 | 448.4 |
分子式 | C23H30BrNO3 |
CAS No. | 50-34-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 198.5 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2302 mL | 11.1508 mL | 22.3015 mL | 55.7538 mL |
5 mM | 0.446 mL | 2.2302 mL | 4.4603 mL | 11.1508 mL | |
10 mM | 0.223 mL | 1.1151 mL | 2.2302 mL | 5.5754 mL | |
20 mM | 0.1115 mL | 0.5575 mL | 1.1151 mL | 2.7877 mL | |
50 mM | 0.0446 mL | 0.223 mL | 0.446 mL | 1.1151 mL | |
100 mM | 0.0223 mL | 0.1115 mL | 0.223 mL | 0.5575 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Propantheline bromide 50-34-0 Neuroscience AChR Urination Propantheline Neopepulsan IBS Inhibitor 溴丙胺太林 mAChR Propantheline Bromide Muscarinic acetylcholine receptor cramps bladder Pro-Banthine Neometantyl bowel dysfunction inhibit inhibitor