Promethazine hydrochloride
编号 T0445L
别名:
Promethazine HCl,
Phenergan
CAS 58-33-3
分子式
C17H20N2S·HCl
分子量
320.88
靶点:
H1 receptor;
α-adrenergic receptor;
Promethazine HCl(NSC-231688), the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
生物活性
产品描述 |
Promethazine HCl(NSC-231688), the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors. |
靶点活性 |
H1 receptor, α-adrenergic receptor, |
体外活性 |
|
体内活性 |
化学信息
分子量 |
320.88 |
分子式 |
C17H20N2S·HCl |
CAS |
58-33-3 |
溶解度 |
DMSO: 18.66 mg/mL (58.15 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
储存条件 |
store at -80°C |
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
1 mg | 5 mg | 10 mg | |
1 mM | 3.116 ml | 15.582 ml | 31.164 ml |
5 mM | 0.623 ml | 3.116 ml | 6.233 ml |
10 mM | 0.312 ml | 1.558 ml | 3.116 ml |
50 mM | 0.062 ml | 0.312 ml | 0.623 ml |