keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Progabide (SL 76002) 是一种 γ-氨基丁酸 (GABA) 受体激动剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 218 | 现货 | ||
5 mg | ¥ 483 | 现货 | ||
10 mg | ¥ 828 | 现货 | ||
25 mg | ¥ 1,660 | 现货 | ||
50 mg | ¥ 2,660 | 现货 | ||
100 mg | ¥ 3,950 | 现货 | ||
200 mg | ¥ 5,510 | 现货 | ||
500 mg | ¥ 8,490 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 547 | 现货 |
产品描述 | Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor. |
体内活性 | Progabide ( 50, 100 and 200 mg/kg) given IP to male Wistar rats enhance the plasma corticosterone levels by 244, 365, and 476% respectively (t=6.44 to12.55, p<0.01). Progabide (10 mg/kg) fails to change the concentration of corticosterone in plasma (t=0.76, N.S.). The increased plasma corticosterone level induced by administration of 200 mg/kg Progabide is evident 30 (t=2.625, p<0.05), 60 (t=13.13, p<0.001) and 120 min (t=4.07, p<0.01) after drug injection, but returns to the control value 240 min after drug injection (t=0.86, N.S.). Compare with the corresponding control, The greatest corticosterone rise is reached 60 min following the administration of Progabide[1]. |
别名 | SL 76002, Halogabide, Gabren, Gabrene |
分子量 | 334.77 |
分子式 | C17H16ClFN2O2 |
CAS No. | 62666-20-0 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (672.1 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.9871 mL | 14.9356 mL | 29.8713 mL | 74.6781 mL |
5 mM | 0.5974 mL | 2.9871 mL | 5.9743 mL | 14.9356 mL | |
10 mM | 0.2987 mL | 1.4936 mL | 2.9871 mL | 7.4678 mL | |
20 mM | 0.1494 mL | 0.7468 mL | 1.4936 mL | 3.7339 mL | |
50 mM | 0.0597 mL | 0.2987 mL | 0.5974 mL | 1.4936 mL | |
100 mM | 0.0299 mL | 0.1494 mL | 0.2987 mL | 0.7468 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Progabide 62666-20-0 Membrane transporter/Ion channel Neuroscience GABA Receptor SL 76002 SL-76002 Halogabide SL76002 Gabren Gabrene Inhibitor inhibitor inhibit